Prenylated xanthones from mangosteen as promising cholinesterase inhibitors and their molecular docking studies.

Khaw, K Y; Choi, S B; Tan, S C; Wahab, H A; Chan, K L; Murugaiyah, V

Khaw, K Y; Choi, S B; Tan, S C; Wahab, H A; Chan, K L; Murugaiyah, V.

Afiliação

Khaw KY; Discipline of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia.
Choi SB; Bioprocess Division, School of Industrial Technology, Universiti Sains Malaysia, 11800 Penang, Malaysia.
Tan SC; Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 Penang, Malaysia.
Wahab HA; Pharmaceutical Design and Simulation (PhDS) Laboratory, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia.
Chan KL; Discipline of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia.
Murugaiyah V; Discipline of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia. Electronic address: vicky@usm.my.

Phytomedicine ; 21(11): 1303-9, 2014 Sep 25.

Article em En | MEDLINE | ID: mdl-25172794

Assuntos

Inibidores da Colinesterase/farmacologia; Garcinia mangostana/química; Xantonas/farmacologia; Simulação de Acoplamento Molecular; Estrutura Molecular; Prenilação; Relação Estrutura-Atividade

Palavras-chave

Acetylcholinesterase; Butyrylcholinesterase; Garcinone C; Molecular docking; α-Mangostin; Î³-Mangostin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Colinesterase / Garcinia mangostana / Xantonas Idioma: En Revista: Phytomedicine Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Malásia

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