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Hyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death.
Qi, Yitao; Wang, Jingxiong; Bomben, Valerie C; Li, De-Pei; Chen, Shao-Rui; Sun, Hao; Xi, Yutao; Reed, John G; Cheng, Jinke; Pan, Hui-Lin; Noebels, Jeffrey L; Yeh, Edward T H.
Afiliação
  • Qi Y; Texas Heart Institute, Houston, TX 77030, USA; Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Wang J; Texas Heart Institute, Houston, TX 77030, USA; Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Bomben VC; Departments of Neurology, Neuroscience, Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Li DP; Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Chen SR; Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Sun H; The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Xi Y; Texas Heart Institute, Houston, TX 77030, USA.
  • Reed JG; Departments of Neurology, Neuroscience, Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Cheng J; Texas Heart Institute, Houston, TX 77030, USA; Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
  • Pan HL; Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Noebels JL; Departments of Neurology, Neuroscience, Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Yeh ET; Texas Heart Institute, Houston, TX 77030, USA; Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: etyeh@mdanderson.org.
Neuron ; 83(5): 1159-71, 2014 Sep 03.
Article em En | MEDLINE | ID: mdl-25189211
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Convulsões / Cisteína Endopeptidases / Morte Súbita / Canais de Potássio KCNQ Idioma: En Revista: Neuron Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Convulsões / Cisteína Endopeptidases / Morte Súbita / Canais de Potássio KCNQ Idioma: En Revista: Neuron Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos