Does current evidence support the use of intraoperative cell salvage in reducing the need for blood transfusion in caesarean section?
Curr Opin Obstet Gynecol
; 26(6): 425-30, 2014 Dec.
Article
em En
| MEDLINE
| ID: mdl-25259949
ABSTRACT
PURPOSE OF REVIEW An important cause of maternal morbidity and direct maternal death is obstetric haemorrhage at caesarean section. Concerns regarding allogeneic blood safety, limited blood supplies and rising health costs have collectively generated enthusiasm for the utility of methods intended to reduce the use of allogeneic blood transfusion in cases of haemorrhage at caesarean section. This can be achieved by intraoperative cell salvage (IOCS). The aim of this review is to summarize and examine the evidence for the efficacy of IOCS during caesarean section, in women at risk of haemorrhage, in reducing the need for allogeneic blood transfusion. RECENT FINDINGS:
The majority of the evidence currently available is from case reports and case series. Although this evidence appears to support the use of IOCS in obstetrics, strong clinical evidence or economic effectiveness from clinical trials are essential to support the routine practice of IOCS in obstetrics.SUMMARY:
Current evidence is limited to reported case series and two small controlled studies. Overall, IOCS may reduce the need for allogeneic blood transfusions during caesarean section. Future large randomized trials are required to assess effectiveness, cost effectiveness and safety. The results of the current ongoing SALVO (A randomised controlled trial of intra-operative cell salvage during caesarean section in women at risk of haemorrhage) trial will shed light on these aspects.
Texto completo:
1
Base de dados:
MEDLINE
Métodos Terapêuticos e Terapias MTCI:
Terapias_biologicas
/
Hemoterapia
Assunto principal:
Transfusão de Sangue Autóloga
/
Cesárea
/
Perda Sanguínea Cirúrgica
/
Medicina Baseada em Evidências
/
Recuperação de Sangue Operatório
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Guideline
/
Risk_factors_studies
Idioma:
En
Revista:
Curr Opin Obstet Gynecol
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Reino Unido