Chemical composition and antioxidant activity of a polar extract of Thymelaea microphylla Coss. et Dur.
Nat Prod Res
; 29(7): 671-5, 2015.
Article
em En
| MEDLINE
| ID: mdl-25422072
ABSTRACT
Thymelaea microphylla Coss. et Dur. (Thymelaeaceae) is a rare medicinal plant endemic to Algeria. In order to continue our studies on this species, herein we report the isolation and characterisation of 20 compounds from a hydroalcoholic extract (EtOH-H2O 73) of the aerial parts. They include monoterpene glucosides (1-3), phenolic acid derivatives (4, 8 and 9), phenylpropanoid glucosides (5 and 6), flavonoids (7, 10 and 11), a benzyl alcohol glucoside (12), ionol glucosides (13-16), lignans (17-19) and a bis-coumarin (20). All the structures were elucidated by spectroscopic methods including 1D and 2D NMR experiments, as well as ESI-MS analysis. Moreover, the extract of T. microphylla showed a significant and concentration-dependent free radical-scavenging activity in vitro, correlated to the presence of phenolic and chlorogenic acid derivatives (8, 9 and 4).
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Base de dados:
MEDLINE
Métodos Terapêuticos e Terapias MTCI:
Terapias_biologicas
Assunto principal:
Fenóis
/
Extratos Vegetais
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Sequestradores de Radicais Livres
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Thymelaeaceae
Idioma:
En
Revista:
Nat Prod Res
Ano de publicação:
2015
Tipo de documento:
Article