Casticin inhibits COX-2 and iNOS expression via suppression of NF-&#954;B and MAPK signaling in lipopolysaccharide-stimulated mouse macrophages.

Liou, Chian-Jiun; Len, Wen-Bin; Wu, Shu-Ju; Lin, Chwan-Fwu; Wu, Xin-Ling; Huang, Wen-Chung

Casticin inhibits COX-2 and iNOS expression via suppression of NF-κB and MAPK signaling in lipopolysaccharide-stimulated mouse macrophages.

Liou, Chian-Jiun; Len, Wen-Bin; Wu, Shu-Ju; Lin, Chwan-Fwu; Wu, Xin-Ling; Huang, Wen-Chung.

Afiliação

Liou CJ; Department of Nursing, Chang Gung University of Science and Technology, 261 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan 333, Taiwan, ROC.
Len WB; Department of Nursing, Chang Gung University of Science and Technology, 261 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan 333, Taiwan, ROC.
Wu SJ; Department of Nutrition and Health Sciences, Chang Gung University of Science and Technology, 261 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan 333, Taiwan, ROC.
Lin CF; Department of Cosmetic Sciences, Chang Gung University of Science and Technology, 261 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan 333, Taiwan, ROC.
Wu XL; Department of Nutrition and Health Sciences, Chang Gung University of Science and Technology, 261 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan 333, Taiwan, ROC.
Huang WC; Department of Nutrition and Health Sciences, Chang Gung University of Science and Technology, 261 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan 333, Taiwan, ROC; Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Kwei-Shan, Tao-Yuan 333, Taiwan, ROC; Research

J Ethnopharmacol ; 158 Pt A: 310-6, 2014 Dec 02.

Article em En | MEDLINE | ID: mdl-25446583

Assuntos

Ciclo-Oxigenase 2/metabolismo; Flavonoides/farmacologia; Lipopolissacarídeos/farmacologia; Sistema de Sinalização das MAP Quinases/efeitos dos fármacos; Macrófagos/efeitos dos fármacos; NF-kappa B/antagonistas & inibidores; Óxido Nítrico Sintase Tipo II/antagonistas & inibidores; Animais; Linhagem Celular; Macrófagos/enzimologia; Macrófagos/metabolismo; Camundongos; NF-kappa B/metabolismo; Óxido Nítrico Sintase Tipo II/metabolismo; Fosforilação; Proteínas Proto-Oncogênicas c-akt/metabolismo

Palavras-chave

Casticin; Inducible nitric oxide synthase; MAPK; NF-κB; Proinflammatory cytokines

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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Assunto principal: Flavonoides / Lipopolissacarídeos / NF-kappa B / Sistema de Sinalização das MAP Quinases / Ciclo-Oxigenase 2 / Óxido Nítrico Sintase Tipo II / Macrófagos Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2014 Tipo de documento: Article

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