A Biopsy-based 17-gene Genomic Prostate Score Predicts Recurrence After Radical Prostatectomy and Adverse Surgical Pathology in a Racially Diverse Population of Men with Clinically Low- and Intermediate-risk Prostate Cancer.

Cullen, Jennifer; Rosner, Inger L; Brand, Timothy C; Zhang, Nan; Tsiatis, Athanasios C; Moncur, Joel; Ali, Amina; Chen, Yongmei; Knezevic, Dejan; Maddala, Tara; Lawrence, H Jeffrey; Febbo, Phillip G; Srivastava, Shiv; Sesterhenn, Isabell A; McLeod, David G

Cullen, Jennifer; Rosner, Inger L; Brand, Timothy C; Zhang, Nan; Tsiatis, Athanasios C; Moncur, Joel; Ali, Amina; Chen, Yongmei; Knezevic, Dejan; Maddala, Tara; Lawrence, H Jeffrey; Febbo, Phillip G; Srivastava, Shiv; Sesterhenn, Isabell A; McLeod, David G.

Afiliação

Cullen J; Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. Electronic address: jcullen@cpdr.org.
Rosner IL; Walter Reed National Military Medical Center, Bethesda, MD, USA.
Brand TC; Madigan Army Medical Center, Tacoma, WA, USA.
Zhang N; Genomic Health, Inc., Redwood City, CA, USA.
Tsiatis AC; Genomic Health, Inc., Redwood City, CA, USA.
Moncur J; Walter Reed National Military Medical Center, Bethesda, MD, USA.
Ali A; Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Chen Y; Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Knezevic D; Genomic Health, Inc., Redwood City, CA, USA.
Maddala T; Genomic Health, Inc., Redwood City, CA, USA.
Lawrence HJ; Genomic Health, Inc., Redwood City, CA, USA.
Febbo PG; Genomic Health, Inc., Redwood City, CA, USA.
Srivastava S; Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Sesterhenn IA; Joint Pathology Center, Silver Spring, MD, USA.
McLeod DG; Walter Reed National Military Medical Center, Bethesda, MD, USA.

Eur Urol ; 68(1): 123-31, 2015 Jul.

Article em En | MEDLINE | ID: mdl-25465337

Assuntos

Biomarcadores Tumorais/genética; Regulação Neoplásica da Expressão Gênica; Recidiva Local de Neoplasia/genética; Neoplasias da Próstata/genética; Adulto; Negro ou Afro-Americano/genética; Idoso; Biópsia com Agulha de Grande Calibre; Estudos de Coortes; Genômica; Humanos; Modelos Logísticos; Masculino; Pessoa de Meia-Idade; Recidiva Local de Neoplasia/patologia; Prognóstico; Modelos de Riscos Proporcionais; Prostatectomia; Neoplasias da Próstata/patologia; Neoplasias da Próstata/cirurgia; Medição de Risco; População Branca/genética

Palavras-chave

Clinical validation; Gene expression; Molecular diagnostic testing; Neoplasm recurrence; Prostate neoplasms

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Recidiva Local de Neoplasia Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Eur Urol Ano de publicação: 2015 Tipo de documento: Article

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