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Synthesis and Biological Evaluation of a Series of 2-((1-substituted-1H-1,2,3-triazol-4-yl)methylthio)-6-(naphthalen-1-ylmethyl)pyrimidin-4(3H)-one As Potential HIV-1 Inhibitors.
Fang, Zengjun; Kang, Dongwei; Zhang, Lingzi; Huang, Boshi; Liu, Huiqing; Pannecouque, Christophe; De Clercq, Erik; Zhan, Peng; Liu, Xinyong.
Afiliação
  • Fang Z; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012, Ji'nan, Shandong, China.
  • Kang D; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012, Ji'nan, Shandong, China.
  • Zhang L; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012, Ji'nan, Shandong, China.
  • Huang B; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012, Ji'nan, Shandong, China.
  • Liu H; Institute of Pharmacology, School of Medicine, Shandong University, 44 West Culture Road, 250012, Ji'nan, Shandong, China.
  • Pannecouque C; Rega Institute for Medical Research, K.U.Leuven, Minderbroedersstraat 10, B-3000, Leuven, Belgium.
  • De Clercq E; Rega Institute for Medical Research, K.U.Leuven, Minderbroedersstraat 10, B-3000, Leuven, Belgium.
  • Zhan P; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012, Ji'nan, Shandong, China.
  • Liu X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012, Ji'nan, Shandong, China.
Chem Biol Drug Des ; 86(4): 614-8, 2015 Oct.
Article em En | MEDLINE | ID: mdl-25626467

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Fármacos Anti-HIV Idioma: En Revista: Chem Biol Drug Des Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Fármacos Anti-HIV Idioma: En Revista: Chem Biol Drug Des Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China