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Silibinin inhibits acetylcholinesterase activity and amyloid ß peptide aggregation: a dual-target drug for the treatment of Alzheimer's disease.
Duan, Songwei; Guan, Xiaoyin; Lin, Runxuan; Liu, Xincheng; Yan, Ying; Lin, Ruibang; Zhang, Tianqi; Chen, Xueman; Huang, Jiaqi; Sun, Xicui; Li, Qingqing; Fang, Shaoliang; Xu, Jun; Yao, Zhibin; Gu, Huaiyu.
Afiliação
  • Duan S; Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China; Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China.
  • Guan X; Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Lin R; Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Liu X; Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Yan Y; Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Lin R; Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China; Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China.
  • Zhang T; Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Chen X; Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Huang J; Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Sun X; Guangzhou Brain and Psychiatric Hospital, Guangzhou, China.
  • Li Q; Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Fang S; Key Lab of High Performance Computing of Guangdong Province, Guangzhou, China.
  • Xu J; Research Center for Drug Discovery and Institute of Human Virology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China.
  • Yao Z; Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Gu H; Department of Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China. Electronic address: gu_huaiyu@yahoo.com.
Neurobiol Aging ; 36(5): 1792-807, 2015 May.
Article em En | MEDLINE | ID: mdl-25771396
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Texto completo: 1 Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas / Plantas_medicinales Assunto principal: Silimarina / Inibidores da Colinesterase / Peptídeos beta-Amiloides / Doença de Alzheimer / Agregação Patológica de Proteínas / Fitoterapia Idioma: En Revista: Neurobiol Aging Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas / Plantas_medicinales Assunto principal: Silimarina / Inibidores da Colinesterase / Peptídeos beta-Amiloides / Doença de Alzheimer / Agregação Patológica de Proteínas / Fitoterapia Idioma: En Revista: Neurobiol Aging Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China