Identification of metabolites of PSORALEAE FRUCTUS in rats by ultra performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry analysis.

Wang, Pei-le; Yao, Zhi-hong; Zhang, Feng-xiang; Shen, Xiu-yu; Dai, Yi; Qin, Ling; Yao, Xin-sheng

Wang, Pei-le; Yao, Zhi-hong; Zhang, Feng-xiang; Shen, Xiu-yu; Dai, Yi; Qin, Ling; Yao, Xin-sheng.

Afiliação

Wang PL; College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Yao ZH; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Zhang FX; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Shen XY; College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Dai Y; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China. Electronic address: daiyi1004@163.com.
Qin L; Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Shatin, N.T. Hong Kong SAR, China.
Yao XS; College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China; Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China. Electronic address: tyaoxs@jnu.edu.cn.

J Pharm Biomed Anal ; 112: 23-35, 2015 Aug 10.

Article em En | MEDLINE | ID: mdl-25951619

Assuntos

Medicamentos de Ervas Chinesas/química; Frutas/química; Psoralea/química; Administração Oral; Animais; Chalcona/química; Cromatografia Líquida de Alta Pressão/métodos; Cumarínicos/química; Interações Medicamentosas; Flavanonas/química; Furocumarinas/química; Isoflavonas/química; Masculino; Medicina Tradicional Chinesa/métodos; Fenóis/química; Extratos Vegetais/química; Ratos; Ratos Sprague-Dawley; Espectrometria de Massas em Tandem/métodos

Palavras-chave

Metabolic fate of multiple components; Metabolic pathways; Metabolite identification; PSORALEAE FRUCTUS; UPLC/Q-TOF-MS

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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas Assunto principal: Medicamentos de Ervas Chinesas / Psoralea / Frutas Tipo de estudo: Diagnostic_studies Idioma: En Revista: J Pharm Biomed Anal Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

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