Dual Effects of Liquiritigenin on the Proliferation of Bone Cells: Promotion of Osteoblast Differentiation and Inhibition of Osteoclast Differentiation.

Uchino, Kaho; Okamoto, Kuniaki; Sakai, Eiko; Yoneshima, Erika; Iwatake, Mayumi; Fukuma, Yutaka; Nishishita, Kazuhisa; Tsukuba, Takayuki

Uchino, Kaho; Okamoto, Kuniaki; Sakai, Eiko; Yoneshima, Erika; Iwatake, Mayumi; Fukuma, Yutaka; Nishishita, Kazuhisa; Tsukuba, Takayuki.

Afiliação

Uchino K; Department of Dental Pharmacology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki, 852-8588, Japan.
Okamoto K; Department of Dental Pharmacology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki, 852-8588, Japan.
Sakai E; Department of Dental Pharmacology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki, 852-8588, Japan.
Yoneshima E; Department of Dental Pharmacology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki, 852-8588, Japan.
Iwatake M; Department of Dental Pharmacology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki, 852-8588, Japan.
Fukuma Y; Department of Dental Pharmacology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki, 852-8588, Japan.
Nishishita K; Department of Dental Pharmacology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki, 852-8588, Japan.
Tsukuba T; Department of Dental Pharmacology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki, 852-8588, Japan.

Phytother Res ; 29(11): 1714-21, 2015 Nov.

Article em En | MEDLINE | ID: mdl-26172226

Assuntos

Flavanonas/farmacologia; Osteoblastos/efeitos dos fármacos; Osteoclastos/efeitos dos fármacos; Animais; Reabsorção Óssea/prevenção & controle; Osso e Ossos; Diferenciação Celular/efeitos dos fármacos; Linhagem Celular; MAP Quinases Reguladas por Sinal Extracelular/metabolismo; Flavonoides/farmacologia; Proteínas Quinases JNK Ativadas por Mitógeno/metabolismo; Camundongos; Osteogênese/efeitos dos fármacos; Osteoporose/tratamento farmacológico; Fosforilação; Ligante RANK/metabolismo

Palavras-chave

differentiation; liquiritigenin; osteoblasts; osteoclasts

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoblastos / Osteoclastos / Flavanonas Idioma: En Revista: Phytother Res Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão

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