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The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of ß Cells.
Hassler, Justin R; Scheuner, Donalyn L; Wang, Shiyu; Han, Jaeseok; Kodali, Vamsi K; Li, Philip; Nguyen, Julie; George, Jenny S; Davis, Cory; Wu, Shengyang P; Bai, Yongsheng; Sartor, Maureen; Cavalcoli, James; Malhi, Harmeet; Baudouin, Gregory; Zhang, Yaoyang; Yates, John R; Itkin-Ansari, Pamela; Volkmann, Niels; Kaufman, Randal J.
Afiliação
  • Hassler JR; Degenerative Diseases Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America; Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America.
  • Scheuner DL; Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America; Lilly Research Laboratories, Eli Lilly & Company, Lilly Corporate Center, Indianapolis, Indiana, United States of America.
  • Wang S; Degenerative Diseases Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America.
  • Han J; Degenerative Diseases Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America.
  • Kodali VK; Degenerative Diseases Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America.
  • Li P; Degenerative Diseases Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America.
  • Nguyen J; Degenerative Diseases Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America.
  • George JS; Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America.
  • Davis C; Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America.
  • Wu SP; Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America.
  • Bai Y; NCIBI Department of Bioinformatics, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America; Department of Biology, Indiana State University, Terre Haute, Indiana, United States of America.
  • Sartor M; NCIBI Department of Bioinformatics, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America.
  • Cavalcoli J; NCIBI Department of Bioinformatics, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America.
  • Malhi H; Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America.
  • Baudouin G; Degenerative Diseases Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America.
  • Zhang Y; Department of Chemical Physiology and Cell Biology, The Scripps Research Institute, La Jolla, California, United States of America.
  • Yates JR; Department of Chemical Physiology and Cell Biology, The Scripps Research Institute, La Jolla, California, United States of America.
  • Itkin-Ansari P; Degenerative Diseases Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America.
  • Volkmann N; Degenerative Diseases Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America.
  • Kaufman RJ; Degenerative Diseases Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America; Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America; Department of Internal Medicine, University of
PLoS Biol ; 13(10): e1002277, 2015 10.
Article em En | MEDLINE | ID: mdl-26469762
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Serina-Treonina Quinases / Processamento Alternativo / Estresse Oxidativo / Proteínas de Ligação a DNA / Endorribonucleases / Células Secretoras de Insulina / Hiperglicemia / Insulina Idioma: En Revista: PLoS Biol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Serina-Treonina Quinases / Processamento Alternativo / Estresse Oxidativo / Proteínas de Ligação a DNA / Endorribonucleases / Células Secretoras de Insulina / Hiperglicemia / Insulina Idioma: En Revista: PLoS Biol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos