Pharmacokinetic and pharmacodynamic herb-drug interaction of Andrographis paniculata (Nees) extract and andrographolide with etoricoxib after oral administration in rats.

Balap, Aishwarya; Atre, Bhagyashri; Lohidasan, Sathiyanarayanan; Sinnathambi, Arulmozhi; Mahadik, Kakasaheb

Balap, Aishwarya; Atre, Bhagyashri; Lohidasan, Sathiyanarayanan; Sinnathambi, Arulmozhi; Mahadik, Kakasaheb.

Afiliação

Balap A; Department of Pharmaceutical Chemistry, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University (BVDU), Pune 411038, India.
Atre B; Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University (BVDU), Pune 411038, India.
Lohidasan S; Department of Pharmaceutical Chemistry, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University (BVDU), Pune 411038, India. Electronic address: pharmsathiya@gmail.com.
Sinnathambi A; Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University (BVDU), Pune 411038, India.
Mahadik K; Department of Pharmaceutical Chemistry, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University (BVDU), Pune 411038, India. Electronic address: krmahadik@redifffmail.com.

J Ethnopharmacol ; 183: 9-17, 2016 May 13.

Article em En | MEDLINE | ID: mdl-26593212

Assuntos

Andrographis/química; Diterpenos/farmacocinética; Interações Ervas-Drogas; Extratos Vegetais/farmacocinética; Piridinas/farmacocinética; Sulfonas/farmacocinética; Administração Oral; Animais; Anti-Inflamatórios/farmacocinética; Anti-Inflamatórios/farmacologia; Antioxidantes/farmacocinética; Antioxidantes/farmacologia; Artrite/tratamento farmacológico; Artrite/metabolismo; Cromatografia Líquida de Alta Pressão; Diterpenos/farmacologia; Etoricoxib; Feminino; Extratos Vegetais/farmacologia; Plantas Medicinais/química; Piridinas/farmacologia; Ratos; Ratos Wistar; Sulfonas/farmacologia

Palavras-chave

Andrographis paniculata extract; Andrographolide; Andrographolide (Pubchem CID: 5318517); Celecoxib (Pubchem CID: 2662); Etoricoxib; Etoricoxib (Pubchem CID: 123619); Herbdrug Interaction; Pharmacodynamics; Pharmacokinetics

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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_unani Medicinas Complementares: Homeopatia Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas Assunto principal: Piridinas / Sulfonas / Extratos Vegetais / Andrographis / Interações Ervas-Drogas / Diterpenos Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Índia

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