Inhibition of tumor growth and metastasis by photoimmunotherapy targeting tumor-associated macrophage in a sorafenib-resistant tumor model.

Zhang, Chenran; Gao, Liquan; Cai, Yuehong; Liu, Hao; Gao, Duo; Lai, Jianhao; Jia, Bing; Wang, Fan; Liu, Zhaofei

Zhang, Chenran; Gao, Liquan; Cai, Yuehong; Liu, Hao; Gao, Duo; Lai, Jianhao; Jia, Bing; Wang, Fan; Liu, Zhaofei.

Afiliação

Zhang C; Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Gao L; Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Cai Y; Division of Medical Sciences, Weifang People's Hospital, Weifang 261000, China.
Liu H; Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Gao D; Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Lai J; Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Jia B; Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Wang F; Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China; Interdisciplinary Laboratory, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Liu Z; Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China. Electronic address: liuzf@bjmu.edu.cn.

Biomaterials ; 84: 1-12, 2016 Apr.

Article em En | MEDLINE | ID: mdl-26803407

Assuntos

Neoplasias da Mama/tratamento farmacológico; Neoplasias da Mama/patologia; Resistencia a Medicamentos Antineoplásicos/efeitos dos fármacos; Imunoterapia/métodos; Macrófagos/metabolismo; Niacinamida/análogos & derivados; Compostos de Fenilureia/uso terapêutico; Fototerapia/métodos; Animais; Morte Celular/efeitos dos fármacos; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Modelos Animais de Doenças; Feminino; Macrófagos/efeitos dos fármacos; Macrófagos/patologia; Camundongos; Camundongos Endogâmicos BALB C; Metástase Neoplásica; Niacinamida/farmacologia; Niacinamida/uso terapêutico; Compostos de Fenilureia/farmacologia; Células RAW 264.7; Sorafenibe

Palavras-chave

Molecular imaging; Photoimmunotherapy; Tumor metastasis; Tumor microenvironment; Tumor-associated macrophage (TAM)

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Texto completo: 1 Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas / Aromoterapia Assunto principal: Compostos de Fenilureia / Fototerapia / Neoplasias da Mama / Niacinamida / Resistencia a Medicamentos Antineoplásicos / Imunoterapia / Macrófagos Tipo de estudo: Risk_factors_studies Idioma: En Revista: Biomaterials Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China

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