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Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice.
Korner, Germaine; Scherer, Tanja; Adamsen, Dea; Rebuffat, Alexander; Crabtree, Mark; Rassi, Anahita; Scavelli, Rossana; Homma, Daigo; Ledermann, Birgit; Konrad, Daniel; Ichinose, Hiroshi; Wolfrum, Christian; Horsch, Marion; Rathkolb, Birgit; Klingenspor, Martin; Beckers, Johannes; Wolf, Eckhard; Gailus-Durner, Valérie; Fuchs, Helmut; Hrabe de Angelis, Martin; Blau, Nenad; Rozman, Jan; Thöny, Beat.
Afiliação
  • Korner G; Division of Metabolism, University Children's Hospital Zürich, Steinwiesstrasse 75, CH-8032, Zürich, Switzerland.
  • Scherer T; Affiliated with the Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zürich, Switzerland.
  • Adamsen D; Children's Research Center (CRC), Zürich, Switzerland.
  • Rebuffat A; Division of Metabolism, University Children's Hospital Zürich, Steinwiesstrasse 75, CH-8032, Zürich, Switzerland.
  • Crabtree M; Affiliated with the Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zürich, Switzerland.
  • Rassi A; Children's Research Center (CRC), Zürich, Switzerland.
  • Scavelli R; Division of Metabolism, University Children's Hospital Zürich, Steinwiesstrasse 75, CH-8032, Zürich, Switzerland.
  • Homma D; Affiliated with the Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zürich, Switzerland.
  • Ledermann B; Children's Research Center (CRC), Zürich, Switzerland.
  • Konrad D; Division of Metabolism, University Children's Hospital Zürich, Steinwiesstrasse 75, CH-8032, Zürich, Switzerland.
  • Ichinose H; BHF Centre of Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, OX3 9DU, Oxford, UK.
  • Wolfrum C; Division of Clinical Chemistry and Biochemistry, University Children's Hospital Zürich, Zürich, Switzerland.
  • Horsch M; Division of Metabolism, University Children's Hospital Zürich, Steinwiesstrasse 75, CH-8032, Zürich, Switzerland.
  • Rathkolb B; Department of Life Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan.
  • Klingenspor M; Division of Animal Facility, University of Zurich, Zürich, Switzerland.
  • Beckers J; Division of Pediatric Endocrinology and Diabetology, University Children's Hospital Zürich, Zürich, Switzerland.
  • Wolf E; Department of Life Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan.
  • Gailus-Durner V; Institute of Food Nutrition and Health, Swiss Federal Institute of Technology Zürich, Zürich, Switzerland.
  • Fuchs H; German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, 85764, Neuherberg, Germany.
  • Hrabe de Angelis M; German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, 85764, Neuherberg, Germany.
  • Blau N; Institute of Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig-Maximilians-Universität München, Feodor-Lynen-Str. 25, 81377, Munich, Germany.
  • Rozman J; German Center for Diabetes Research (DZD), Ingolstädter Landstrasse 1, 85764, Neuherberg, Germany.
  • Thöny B; Molecular Nutritional Medicine, Else Kröner-Fresenius Center, Technische Universität München, Am Forum 8, 85354, Freising-Weihenstephan, Germany.
J Inherit Metab Dis ; 39(2): 309-19, 2016 Mar.
Article em En | MEDLINE | ID: mdl-26830550
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biopterinas / Tecido Adiposo / Fósforo-Oxigênio Liases / Distribuição da Gordura Corporal / Obesidade Abdominal Idioma: En Revista: J Inherit Metab Dis Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biopterinas / Tecido Adiposo / Fósforo-Oxigênio Liases / Distribuição da Gordura Corporal / Obesidade Abdominal Idioma: En Revista: J Inherit Metab Dis Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça