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HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival.
Stegen, Steve; van Gastel, Nick; Eelen, Guy; Ghesquière, Bart; D'Anna, Flora; Thienpont, Bernard; Goveia, Jermaine; Torrekens, Sophie; Van Looveren, Riet; Luyten, Frank P; Maxwell, Patrick H; Wielockx, Ben; Lambrechts, Diether; Fendt, Sarah-Maria; Carmeliet, Peter; Carmeliet, Geert.
Afiliação
  • Stegen S; Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, KU Leuven, 3000 Leuven, Belgium; Prometheus, Division of Skeletal Tissue Engineering, KU Leuven, 3000 Leuven, Belgium.
  • van Gastel N; Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, KU Leuven, 3000 Leuven, Belgium; Prometheus, Division of Skeletal Tissue Engineering, KU Leuven, 3000 Leuven, Belgium.
  • Eelen G; Laboratory of Angiogenesis & Vascular Metabolism, Vesalius Research Center, Department of Oncology, KU Leuven/VIB, 3000 Leuven, Belgium.
  • Ghesquière B; Laboratory of Angiogenesis & Vascular Metabolism, Vesalius Research Center, Department of Oncology, KU Leuven/VIB, 3000 Leuven, Belgium.
  • D'Anna F; Laboratory of Translational Genetics, Vesalius Research Center, Department of Oncology, KU Leuven/VIB, 3000 Leuven, Belgium.
  • Thienpont B; Laboratory of Translational Genetics, Vesalius Research Center, Department of Oncology, KU Leuven/VIB, 3000 Leuven, Belgium.
  • Goveia J; Laboratory of Angiogenesis & Vascular Metabolism, Vesalius Research Center, Department of Oncology, KU Leuven/VIB, 3000 Leuven, Belgium.
  • Torrekens S; Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, KU Leuven, 3000 Leuven, Belgium.
  • Van Looveren R; Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, KU Leuven, 3000 Leuven, Belgium.
  • Luyten FP; Prometheus, Division of Skeletal Tissue Engineering, KU Leuven, 3000 Leuven, Belgium; Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium.
  • Maxwell PH; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XU, UK.
  • Wielockx B; Heisenberg Research Group, Department of Clinical Pathobiochemistry, Institute for Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, 01069 Dresden, Germany.
  • Lambrechts D; Laboratory of Translational Genetics, Vesalius Research Center, Department of Oncology, KU Leuven/VIB, 3000 Leuven, Belgium.
  • Fendt SM; Laboratory of Cellular Metabolism and Metabolic Regulation, Vesalius Research Center, Department of Oncology, KU Leuven/VIB, 3000 Leuven, Belgium.
  • Carmeliet P; Laboratory of Angiogenesis & Vascular Metabolism, Vesalius Research Center, Department of Oncology, KU Leuven/VIB, 3000 Leuven, Belgium.
  • Carmeliet G; Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, KU Leuven, 3000 Leuven, Belgium; Prometheus, Division of Skeletal Tissue Engineering, KU Leuven, 3000 Leuven, Belgium. Electronic address: geert.carmeliet@med.kuleuven.be.
Cell Metab ; 23(2): 265-79, 2016 Feb 09.
Article em En | MEDLINE | ID: mdl-26863487

Texto completo: 1 Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Terapias_energeticas / Bioenergetica Assunto principal: Osteócitos / Metabolismo Energético / Subunidade alfa do Fator 1 Induzível por Hipóxia / Glutamina / Glicogênio / Homeostase Idioma: En Revista: Cell Metab Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Bélgica

Texto completo: 1 Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Terapias_energeticas / Bioenergetica Assunto principal: Osteócitos / Metabolismo Energético / Subunidade alfa do Fator 1 Induzível por Hipóxia / Glutamina / Glicogênio / Homeostase Idioma: En Revista: Cell Metab Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Bélgica