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Diosgenin induces ROS-dependent autophagy and cytotoxicity via mTOR signaling pathway in chronic myeloid leukemia cells.
Jiang, Shanshan; Fan, Jiajun; Wang, Qian; Ju, Dianwen; Feng, Meiqing; Li, Jiyang; Guan, Zhong-Bin; An, Duopeng; Wang, Xin; Ye, Li.
Afiliação
  • Jiang S; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Fan J; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Wang Q; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Ju D; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Feng M; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Li J; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Guan ZB; Shanghai Institute For Food And Drug Control, Shanghai, China.
  • An D; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Wang X; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Ye L; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China. Electronic address: yelil@fudan.edu.cn.
Phytomedicine ; 23(3): 243-52, 2016 Mar 15.
Article em En | MEDLINE | ID: mdl-26969378
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Leucemia Mielogênica Crônica BCR-ABL Positiva / Transdução de Sinais / Espécies Reativas de Oxigênio / Diosgenina / Serina-Treonina Quinases TOR Idioma: En Revista: Phytomedicine Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Leucemia Mielogênica Crônica BCR-ABL Positiva / Transdução de Sinais / Espécies Reativas de Oxigênio / Diosgenina / Serina-Treonina Quinases TOR Idioma: En Revista: Phytomedicine Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China