Two standardized fractions of Gardenia jasminoides Ellis with rapid antidepressant effects are differentially associated with BDNF up-regulation in the hippocampus.

Ren, Li; Tao, Weiwei; Zhang, Hailou; Xue, Wenda; Tang, Juanjuan; Wu, Ruyan; Xia, Baomei; Wu, Haoxing; Chen, Gang

Ren, Li; Tao, Weiwei; Zhang, Hailou; Xue, Wenda; Tang, Juanjuan; Wu, Ruyan; Xia, Baomei; Wu, Haoxing; Chen, Gang.

Afiliação

Ren L; Center for Translational Systems Biology and Neuroscience, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Laboratory of Integrative Biomedicine for Brain Diseases, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanj
Tao W; Center for Translational Systems Biology and Neuroscience, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Laboratory of Integrative Biomedicine for Brain Diseases, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanj
Zhang H; Center for Translational Systems Biology and Neuroscience, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Laboratory of Integrative Biomedicine for Brain Diseases, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanj
Xue W; Center for Translational Systems Biology and Neuroscience, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Laboratory of Integrative Biomedicine for Brain Diseases, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanj
Tang J; Center for Translational Systems Biology and Neuroscience, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Laboratory of Integrative Biomedicine for Brain Diseases, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanj
Wu R; Center for Translational Systems Biology and Neuroscience, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Laboratory of Integrative Biomedicine for Brain Diseases, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanj
Xia B; Center for Translational Systems Biology and Neuroscience, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Laboratory of Integrative Biomedicine for Brain Diseases, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanj
Wu H; Center for Translational Systems Biology and Neuroscience, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Laboratory of Integrative Biomedicine for Brain Diseases, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanj
Chen G; Center for Translational Systems Biology and Neuroscience, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Laboratory of Integrative Biomedicine for Brain Diseases, School of Basic Biomedical Science, Nanjing University of Chinese Medicine, Nanj

J Ethnopharmacol ; 187: 66-73, 2016 Jul 01.

Article em En | MEDLINE | ID: mdl-27108051

Assuntos

Antidepressivos/uso terapêutico; Depressão/tratamento farmacológico; Gardenia; Extratos Vegetais/uso terapêutico; Estresse Psicológico/tratamento farmacológico; Animais; Antidepressivos/farmacologia; Fator Neurotrófico Derivado do Encéfalo/metabolismo; Depressão/metabolismo; Modelos Animais de Doenças; Elevação dos Membros Posteriores; Hipocampo/efeitos dos fármacos; Hipocampo/metabolismo; Masculino; Camundongos; Fitoterapia; Extratos Vegetais/farmacologia; Receptor trkB/metabolismo; Estresse Psicológico/metabolismo; Natação; Regulação para Cima/efeitos dos fármacos

Palavras-chave

BDNF; Chemical fractions; Chronic stress; Gardenia Jasminoides Ellis; Geniposide (Pubchem CID: 107848); Gerdenoside (Pubchem CID: 442423); Rapid antidepressant; TrkB; crocetin (Pubchem CID: 5281232); crocin-1(Pubchem CID: 5281233); crocin-2 (Pubchem CID: 91746171); genipin (Pubchem CID:442424); geniposidic acid (Pubchem CID: 443354)

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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas / Aromoterapia Assunto principal: Estresse Psicológico / Extratos Vegetais / Gardenia / Depressão / Antidepressivos Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2016 Tipo de documento: Article

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