Screening Vaccine Formulations in Fresh Human Whole Blood.

Hakimi, Jalil; Aboutorabian, Sepideh; To, Frederick; Ausar, Salvador F; Rahman, Nausheen; Brookes, Roger H

Hakimi, Jalil; Aboutorabian, Sepideh; To, Frederick; Ausar, Salvador F; Rahman, Nausheen; Brookes, Roger H.

Afiliação

Hakimi J; Bioprocess Research and Development, Sanofi Pasteur, 1755 Steeles Avenue West, Toronto, Canada, M2R 3T4.
Aboutorabian S; Bioprocess Research and Development, Sanofi Pasteur, 1755 Steeles Avenue West, Toronto, Canada, M2R 3T4.
To F; Bioprocess Research and Development, Sanofi Pasteur, 1755 Steeles Avenue West, Toronto, Canada, M2R 3T4.
Ausar SF; Bioprocess Research and Development, Sanofi Pasteur, 1755 Steeles Avenue West, Toronto, Canada, M2R 3T4.
Rahman N; Bioprocess Research and Development, Sanofi Pasteur, 1755 Steeles Avenue West, Toronto, Canada, M2R 3T4.
Brookes RH; Bioprocess Research and Development, Sanofi Pasteur, 1755 Steeles Avenue West, Toronto, Canada, M2R 3T4. roger.brookes@sanofipasteur.com.

Methods Mol Biol ; 1494: 295-304, 2017.

Article em En | MEDLINE | ID: mdl-27718203

Assuntos

Sangue; Composição de Medicamentos; Vacinas; Avaliação Pré-Clínica de Medicamentos/métodos; Humanos; Vacinas/química; Vacinas/farmacologia

Palavras-chave

Adjuvant modulation; Cytokine signature; Functionality; Immunomodulation; Vaccine; Vaccine formulation screening; Whole-blood assay; hWB human whole blood

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Base de dados: MEDLINE Assunto principal: Sangue / Vacinas / Composição de Medicamentos Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Revista: Methods Mol Biol Ano de publicação: 2017 Tipo de documento: Article

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