Alkaloids and Phenolic Compounds from Sida rhombifolia L. (Malvaceae) and Vasorelaxant Activity of Two Indoquinoline Alkaloids.
Molecules
; 22(1)2017 Jan 06.
Article
em En
| MEDLINE
| ID: mdl-28067836
ABSTRACT
The follow-up of phytochemical and pharmacological studies of Sida rhombifolia L. (Malvaceae) aims to strengthen the chemosystematics and pharmacology of Sida genera and support the ethnopharmacological use of this species as hypotensive herb. The present work reports phytoconstituents isolated and identified from aerial parts of S. rhombifolia by using chromatographic and spectroscopic methods. The study led to the isolation of scopoletin (1), scoporone (2), ethoxy-ferulate (3), kaempferol (4), kaempferol-3-O-ß-d-glycosyl-6''-α-d-rhamnose (5), quindolinone (6), 11-methoxy-quindoline (7), quindoline (8), and the cryptolepine salt (9). The alkaloids quindolinone (6) and cryptolepine salt (9) showed vasorelaxant activity in rodent isolated mesenteric arteries.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fenóis
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Vasodilatadores
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Malvaceae
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Alcaloides
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Compostos Fitoquímicos
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Anti-Hipertensivos
Idioma:
En
Revista:
Molecules
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Brasil