Antibacterial Nerol Cinnamates from the Australian Plant Eremophila longifolia.
J Nat Prod
; 80(4): 1178-1181, 2017 04 28.
Article
em En
| MEDLINE
| ID: mdl-28257200
ABSTRACT
Two new antimicrobial agents, neryl ferulate (1) and neryl p-coumarate (2), were identified using bioassay-guided isolation from the leaves of Eremophila longifolia, which is a medicinal plant used by some Australian Aboriginal communities. Although gradual autoxidation of the nerol subunit hindered the initial attempts to purify and characterize 1 and 2, it was found that the autoxidation could be stopped through storage under argon at -20 °C. Biological evaluation showed that neryl ferulate (1) had moderate activity against various Gram-positive bacteria, while neryl p-coumarate (2) was active only against Enterococcus faecium.
Texto completo:
1
Base de dados:
MEDLINE
Métodos Terapêuticos e Terapias MTCI:
Terapias_biologicas
Assunto principal:
Plantas Medicinais
/
Cinamatos
/
Ácidos Cumáricos
/
Eremophila (Planta)
/
Anti-Infecciosos
/
Antibacterianos
País/Região como assunto:
Oceania
Idioma:
En
Revista:
J Nat Prod
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Austrália