Small cryotherapy devices for the treatment of skin warts.
J Dermatolog Treat
; 28(8): 745-750, 2017 Dec.
Article
em En
| MEDLINE
| ID: mdl-28475390
ABSTRACT
STUDY PURPOSE:
Effectiveness of cryotherapy on skin wart models. MATERIALS ANDMETHODS:
Two small cryotherapy devices, Wartner and Wortie, were administered for 10â³-60â³ on tomatoes and potatoes used as skin wart models. Frozen surface and depth were evaluated by standardized photography and computer analysis. Tissue temperature at depths of 0.1-10 mm was assessed by an electronic thermometer during treatment.RESULTS:
Cryotherapy induced a transient freezing of the tomato surface. The devices produced similar tomato tissue temperature reduction at all depths examined. At 5 mm, Wortie induced lower tissue temperatures than Wartner. Both devices induced potato tissue destruction to a depth of 0.5-1.2 mm at 40â³ and 50â³. Wartner induced a maximum destruction at 40â³, Wortie led to a partially linear destruction depth with freezing time. The devices produced similar reduction of potato tissue temperature at all depths tested. Wartner induced more rapidly lower temperatures (1.5 mm, 10â³, p = .001). Wortie induced lower tissue temperatures with time (0.1 mm, 50â³, p = .025; 60â³, p = .039; 5 mm, 60â³, p = .05). None of the devices reached the lethal temperature of -22 °C.CONCLUSIONS:
Both cryotherapy devices produced sufficient tissue damage, at least in the potatoes, to a depth of 0.5-1.2 mm when applied for 40â³ (commercially proposed time).Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Métodos Terapêuticos e Terapias MTCI:
Plantas_medicinales
Assunto principal:
Verrugas
/
Crioterapia
/
Modelos Biológicos
Idioma:
En
Revista:
J Dermatolog Treat
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Alemanha