Tanshinone IIA Inhibits ß-Catenin Nuclear Translocation and IGF-2R Activation via Estrogen Receptors to Suppress Angiotensin II-Induced H9c2 Cardiomyoblast Cell Apoptosis.

Chen, Ya-Fang; Day, Cecilia Hsuan; Lee, Nien-Hung; Chen, Yu-Feng; Yang, Jaw-Ji; Lin, Chih-Hsueh; Chen, Ray-Jade; Rajendran, Peramaiyan; Viswanadha, Vijaya Padma; Huang, Chih-Yang

Chen, Ya-Fang; Day, Cecilia Hsuan; Lee, Nien-Hung; Chen, Yu-Feng; Yang, Jaw-Ji; Lin, Chih-Hsueh; Chen, Ray-Jade; Rajendran, Peramaiyan; Viswanadha, Vijaya Padma; Huang, Chih-Yang.

Afiliação

Chen YF; Graduate Institute of Basic Medical Science, China Medical University, Taichung 40402, Taiwan.
Day CH; Department of Obstetrics and Gynecology, Taichung Veteran's General Hospital, Taichung 40705,Taiwan.
Lee NH; Department of Nursing, MeiHo University, Pingtung 91202, Taiwan.
Chen YF; Graduate Institute of Basic Medical Science, China Medical University, Taichung 40402, Taiwan.
Yang JJ; Section of Cardiology, Yuan Rung Hospital, Yuanlin, Taiwan.
Lin CH; 5Institute of Oral Sciences, College of Oral Medicine, Chung Shan Medical University, Taichung40201, Taiwan.
Chen RJ; Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan.
Rajendran P; School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan.
Viswanadha VP; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei11031, Taiwan.
Huang CY; Graduate Institute of Basic Medical Science, China Medical University, Taichung 40402, Taiwan.

Int J Med Sci ; 14(12): 1284-1291, 2017.

Article em En | MEDLINE | ID: mdl-29104486

Assuntos

Abietanos/farmacologia; Angiotensina II/metabolismo; Apoptose/efeitos dos fármacos; Medicamentos de Ervas Chinesas/farmacologia; Miócitos Cardíacos/fisiologia; Abietanos/uso terapêutico; Animais; Cardiomiopatia Hipertrófica/tratamento farmacológico; Cardiomiopatia Hipertrófica/patologia; Linhagem Celular; Núcleo Celular/metabolismo; Medicamentos de Ervas Chinesas/uso terapêutico; Humanos; Fosforilação; Transporte Proteico/efeitos dos fármacos; Ratos; Receptor IGF Tipo 2/metabolismo; Receptores de Estrogênio/metabolismo; Salvia miltiorrhiza; Transdução de Sinais/efeitos dos fármacos; beta Catenina/metabolismo

Palavras-chave

Angiotensin II; Estrogen receptors; H9c2 Cardiomyoblasts; Insulin-like Growth Factor-2 Receptor; Tanshinone IIA.; ß-Catenin

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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Assunto principal: Angiotensina II / Medicamentos de Ervas Chinesas / Apoptose / Miócitos Cardíacos / Abietanos Idioma: En Revista: Int J Med Sci Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Taiwan

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