Metabolites identificaion of two bioactive constituents in Trollius ledebourii in rats using ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry.

Liao, Man; Cheng, Xiaoye; Diao, Xinpeng; Sun, Yupeng; Zhang, Lantong

Liao, Man; Cheng, Xiaoye; Diao, Xinpeng; Sun, Yupeng; Zhang, Lantong.

Afiliação

Liao M; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University,361 East Zhongshan Road, Shijiazhuang, Hebei 050017, PR China.
Cheng X; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University,361 East Zhongshan Road, Shijiazhuang, Hebei 050017, PR China.
Diao X; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University,361 East Zhongshan Road, Shijiazhuang, Hebei 050017, PR China.
Sun Y; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University,361 East Zhongshan Road, Shijiazhuang, Hebei 050017, PR China.
Zhang L; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University,361 East Zhongshan Road, Shijiazhuang, Hebei 050017, PR China. Electronic address: zhanglantong@263.net.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1068-1069: 297-312, 2017 Nov 15.

Article em En | MEDLINE | ID: mdl-29127056

Assuntos

Apigenina/metabolismo; Cromatografia Líquida de Alta Pressão/métodos; Flavonoides/metabolismo; Glucosídeos/metabolismo; Espectrometria de Massas/métodos; Animais; Apigenina/análise; Apigenina/química; Medicamentos de Ervas Chinesas; Flavonoides/análise; Flavonoides/química; Glucosídeos/análise; Glucosídeos/química; Masculino; Microssomos Hepáticos/metabolismo; Modelos Moleculares; Oxirredução; Ranunculaceae; Ratos; Ratos Sprague-Dawley

Palavras-chave

In vitro; In vivo; Metabolites; Orientin; UHPLC-Q-TOF-MS; Vitexin

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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Assunto principal: Espectrometria de Massas / Flavonoides / Cromatografia Líquida de Alta Pressão / Apigenina / Glucosídeos Tipo de estudo: Diagnostic_studies Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Ano de publicação: 2017 Tipo de documento: Article

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