Prospective studies of the efficacy and safety of the picosecond 755, 1,064, and 532 nm lasers for the treatment of infraorbital dark circles.
Lasers Surg Med
; 50(1): 45-50, 2018 01.
Article
em En
| MEDLINE
| ID: mdl-29135036
ABSTRACT
BACKGROUND:
Infraorbital dark circles result from a combination of factors. The fractionated picosecond 755 nm alexandrite laser and dual wavelength picosecond NdYAG laser have not been examined as a method of addressing infraorbital hyperpigmentation.OBJECTIVE:
To determine the efficacy and safety of treatment of infraorbital dark circles using fractionated picosecond 755 nm and dual wavelength picosecond NdYAG laser. METHODS AND MATERIALS These trials did not utilize a comparative design; rather, these were separate, prospective, open-label, evaluator-blinded trials utilizing two treatment regimens (i) 19 adult subjects were treated in a single session with the dual wavelengths of 532 nm and 1,064 nm in consecutive passes using the fractionated lens; (ii) 10 adult subjects were treated using the picosecond 755 nm laser via the fractionated lens in three treatment sessions at 3 week intervals. Subjects in both studies were followed-up for blinded-investigator assessment of infraorbital hyperpigmentation, adverse events, and improvement compared to baseline.RESULTS:
The dual wavelength picosecond NdYAG laser, blinded-investigator assessment did not demonstrate a significant improvement in infraorbital hyperpigmentation at day 60 (P = 0.16). The picosecond 755 nm alexandrite laser significantly improved infraorbital hyperpigmentation by day 42, with improvement maintained through day 132 (P = 0.07 and 0.00001, respectively). Adverse events were mild and temporary.CONCLUSION:
A single treatment with the fractionated picosecond 1,064/532 nm lasers did not produce a significant improvement in infraorbital hyperpigmentation. A series of three treatments with the fractionated picosecond 755 nm laser resulted in significant improvement in hyperpigmentation. Lasers Surg. Med. 5045-50, 2018. © 2017 Wiley Periodicals, Inc.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Métodos Terapêuticos e Terapias MTCI:
Terapias_energeticas
Assunto principal:
Hiperpigmentação
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Terapia com Luz de Baixa Intensidade
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Dermatoses Faciais
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Lasers de Estado Sólido
Tipo de estudo:
Clinical_trials
/
Observational_studies
Idioma:
En
Revista:
Lasers Surg Med
Ano de publicação:
2018
Tipo de documento:
Article