The downregulation of c-Myc and its target gene hTERT is associated with the antiproliferative effects of baicalin on HL-60 cells.

Ren, Xia; Zhang, Zhiyong; Tian, Jing; Wang, Hengxiao; Song, Guanhua; Guo, Qiang; Tian, Jing; Han, Yang; Liao, Qiong; Liu, Guoqiang; Ding, Huifang; Jiang, Guosheng

Ren, Xia; Zhang, Zhiyong; Tian, Jing; Wang, Hengxiao; Song, Guanhua; Guo, Qiang; Tian, Jing; Han, Yang; Liao, Qiong; Liu, Guoqiang; Ding, Huifang; Jiang, Guosheng.

Afiliação

Ren X; Key Laboratory for Rare and Uncommon Diseases of Shandong and Key Laboratory for Tumor Immunology and Chinese Medicine Immunology of Shandong, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.
Zhang Z; Key Laboratory for Rare and Uncommon Diseases of Shandong and Key Laboratory for Tumor Immunology and Chinese Medicine Immunology of Shandong, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.
Tian J; Laboratory Department, People's Hospital of Zhangqiu, Zhangqiu, Shandong 250200, P.R. China.
Wang H; Key Laboratory for Rare and Uncommon Diseases of Shandong and Key Laboratory for Tumor Immunology and Chinese Medicine Immunology of Shandong, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.
Song G; Key Laboratory for Rare and Uncommon Diseases of Shandong and Key Laboratory for Tumor Immunology and Chinese Medicine Immunology of Shandong, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.
Guo Q; Key Laboratory for Rare and Uncommon Diseases of Shandong and Key Laboratory for Tumor Immunology and Chinese Medicine Immunology of Shandong, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.
Tian J; Key Laboratory for Rare and Uncommon Diseases of Shandong and Key Laboratory for Tumor Immunology and Chinese Medicine Immunology of Shandong, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.
Han Y; Key Laboratory for Rare and Uncommon Diseases of Shandong and Key Laboratory for Tumor Immunology and Chinese Medicine Immunology of Shandong, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.
Liao Q; Key Laboratory for Rare and Uncommon Diseases of Shandong and Key Laboratory for Tumor Immunology and Chinese Medicine Immunology of Shandong, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.
Liu G; Department of Hematology, Shengli Oilfield Central Hospital, Dongying, Shandong 257034, P.R. China.
Ding H; Department of Hematology, Shengli Oilfield Central Hospital, Dongying, Shandong 257034, P.R. China.
Jiang G; Key Laboratory for Rare and Uncommon Diseases of Shandong and Key Laboratory for Tumor Immunology and Chinese Medicine Immunology of Shandong, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.

Oncol Lett ; 14(6): 6833-6840, 2017 Dec.

Article em En | MEDLINE | ID: mdl-29163703

Palavras-chave

HL-60 cells; Myc proto-oncogene protein; apoptosis; baicalin; caspases; extrinsic pathway; human telomerase reverse transcriptase; proliferation

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Oncol Lett Ano de publicação: 2017 Tipo de documento: Article