Inhibition of Glucose Transport by Tomatoside A, a Tomato Seed Steroidal Saponin, through the Suppression of GLUT2 Expression in Caco-2 Cells.

Li, Baorui; Terazono, Yusuke; Hirasaki, Naoto; Tatemichi, Yuki; Kinoshita, Emiko; Obata, Akio; Matsui, Toshiro

Li, Baorui; Terazono, Yusuke; Hirasaki, Naoto; Tatemichi, Yuki; Kinoshita, Emiko; Obata, Akio; Matsui, Toshiro.

Afiliação

Li B; Department of Bioscience and Biotechnology, Division of Bioresource and Bioenvironmental Sciences, Faculty of Agriculture, Graduated School of Kyushu University , 6-10-1 Hakozaki, Fukuoka 812-8581, Japan.
Terazono Y; Department of Bioscience and Biotechnology, Division of Bioresource and Bioenvironmental Sciences, Faculty of Agriculture, Graduated School of Kyushu University , 6-10-1 Hakozaki, Fukuoka 812-8581, Japan.
Hirasaki N; Department of Bioscience and Biotechnology, Division of Bioresource and Bioenvironmental Sciences, Faculty of Agriculture, Graduated School of Kyushu University , 6-10-1 Hakozaki, Fukuoka 812-8581, Japan.
Tatemichi Y; Research & Development Division, Kikkoman Co. , 399 Noda, Chiba 278-0037, Japan.
Kinoshita E; Research & Development Division, Kikkoman Co. , 399 Noda, Chiba 278-0037, Japan.
Obata A; Research & Development Division, Kikkoman Co. , 399 Noda, Chiba 278-0037, Japan.
Matsui T; Department of Bioscience and Biotechnology, Division of Bioresource and Bioenvironmental Sciences, Faculty of Agriculture, Graduated School of Kyushu University , 6-10-1 Hakozaki, Fukuoka 812-8581, Japan.

J Agric Food Chem ; 66(6): 1428-1434, 2018 Feb 14.

Article em En | MEDLINE | ID: mdl-29355315

Assuntos

Transportador de Glucose Tipo 2/metabolismo; Glucose/metabolismo; Glicosídeos/farmacologia; Extratos Vegetais/farmacologia; Solanum lycopersicum/química; Transporte Biológico/efeitos dos fármacos; Células CACO-2; Transportador de Glucose Tipo 2/genética; Humanos; Proteína 2 Associada à Farmacorresistência Múltipla; Proteínas Associadas à Resistência a Múltiplos Medicamentos/genética; Proteínas Associadas à Resistência a Múltiplos Medicamentos/metabolismo; Saponinas/farmacologia; Sementes/química

Palavras-chave

ASBT; GLUT2; MRP2; glucose transport; tomatoside A

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Solanum lycopersicum / Transportador de Glucose Tipo 2 / Glucose / Glicosídeos Idioma: En Revista: J Agric Food Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão

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