Evidence for Shikonin acting as an active inhibitor of human carboxylesterases 2: Implications for herb-drug combination.

Li, Jia-Nan; Cao, Yun-Feng; He, Rong-Rong; Ge, Guang-Bo; Guo, Bin; Wu, Jing-Jing

Li, Jia-Nan; Cao, Yun-Feng; He, Rong-Rong; Ge, Guang-Bo; Guo, Bin; Wu, Jing-Jing.

Afiliação

Li JN; Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Cao YF; Department of Pharmacy, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, 121001, China.
He RR; Key Laborotary of Liaoning Tumor Clinical Metabolomics, Jinzhou, 121001, China.
Ge GB; RSKT Biopharma Inc., Dalian, 116023, China.
Guo B; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Guangzhou, 510632, China.
Wu JJ; Institute of Interdisciplinary Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.

Phytother Res ; 32(7): 1311-1319, 2018 Jul.

Article em En | MEDLINE | ID: mdl-29468758

Assuntos

Carboxilesterase/efeitos dos fármacos; Combinação de Medicamentos; Naftoquinonas/uso terapêutico; Plantas Medicinais/química; Humanos; Naftoquinonas/farmacologia

Palavras-chave

CPT-11; Shikonin; hCE2; herb-drug interactions

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Texto completo: 1 Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas / Plantas_medicinales Assunto principal: Plantas Medicinais / Naftoquinonas / Carboxilesterase / Combinação de Medicamentos Tipo de estudo: Prognostic_studies Idioma: En Revista: Phytother Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

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