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Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis.
Vajen, Tanja; Koenen, Rory R; Werner, Isabella; Staudt, Mareike; Projahn, Delia; Curaj, Adelina; Sönmez, Tolga Taha; Simsekyilmaz, Sakine; Schumacher, David; Möllmann, Julia; Hackeng, Tilman M; Hundelshausen, Philipp von; Weber, Christian; Liehn, Elisa A.
Afiliação
  • Vajen T; Cardiovascular Research Institute Maastricht (CARIM), Department of Biochemistry, Maastricht University, Maastricht, The Netherlands.
  • Koenen RR; Cardiovascular Research Institute Maastricht (CARIM), Department of Biochemistry, Maastricht University, Maastricht, The Netherlands. r.koenen@maastrichtuniversity.nl.
  • Werner I; Institute for Cardiovascular Prevention (IPEK), LMU Munich, Munich, Germany. r.koenen@maastrichtuniversity.nl.
  • Staudt M; Institute for Molecular Cardiovascular Research (IMCAR), RWTH Aachen University, Aachen, Germany.
  • Projahn D; Institute for Molecular Cardiovascular Research (IMCAR), RWTH Aachen University, Aachen, Germany.
  • Curaj A; Institute for Cardiovascular Prevention (IPEK), LMU Munich, Munich, Germany.
  • Sönmez TT; Institute for Molecular Cardiovascular Research (IMCAR), RWTH Aachen University, Aachen, Germany.
  • Simsekyilmaz S; Institute for Molecular Cardiovascular Research (IMCAR), RWTH Aachen University, Aachen, Germany.
  • Schumacher D; Department of Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany.
  • Möllmann J; Victor Babes National Institute of Pathology, Bucharest, Romania.
  • Hackeng TM; Institute for Molecular Cardiovascular Research (IMCAR), RWTH Aachen University, Aachen, Germany.
  • Hundelshausen PV; Department of Oral and Maxillofacial Surgery, Karlsruhe City Hospital of Freiburg University, Freiburg, Germany.
  • Weber C; Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Liehn EA; Institute for Molecular Cardiovascular Research (IMCAR), RWTH Aachen University, Aachen, Germany.
Sci Rep ; 8(1): 10647, 2018 Jul 13.
Article em En | MEDLINE | ID: mdl-30006564

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Fator Plaquetário 4 / Cardiotônicos / Traumatismo por Reperfusão Miocárdica / Quimiocina CCL5 / Multimerização Proteica / Infarto do Miocárdio Tipo de estudo: Prognostic_studies Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Fator Plaquetário 4 / Cardiotônicos / Traumatismo por Reperfusão Miocárdica / Quimiocina CCL5 / Multimerização Proteica / Infarto do Miocárdio Tipo de estudo: Prognostic_studies Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Holanda