Dietary organic selenium addition and accumulation of toxic and essential trace elements in liver and meat of growing rabbits.

The effects of dietary organic selenium (Se) addition at 0.1, 0.5 and 2.5 mg/kg vs. an unsupplemented basal diet (BD) on the accumulation of some toxic and essential trace elements were studied in the liver and muscle tissues of growing rabbits. Dietary Se addition increased liver and muscle Se concentration linearly (P < .001), and decreased linearly Cd, As, Ni and Cr (P < .001) in liver, as well as As (P < .01) and Cd (P < .001) in muscle. Muscle Cu and Zn contents were significantly lower (P < .05) in rabbits fed 2.5 mg Se/kg diet compared to the other 3 groups. Selenium was negatively correlated with Cr, Ni, Cd and As (P < .01) in liver, and with Cu (P < .05) and Cd (P < .01) in muscle. In conclusion, dietary Se supplementation decreased the accumulation of toxic (Cd and As) and potentially toxic (Cr and Ni) trace elements in rabbits. However, at excessive quantities may negatively affect essential trace elements.