A randomised, double-blind, placebo-controlled parallel trial of closed-loop infraslow brain training in food addiction.
Sci Rep
; 8(1): 11659, 2018 08 03.
Article
em En
| MEDLINE
| ID: mdl-30076365
ABSTRACT
The posterior cingulate cortex (PCC) is involved in food craving in obese food addicted individuals. This randomised, double-blind, placebo-controlled parallel study explored the potential therapeutic effects of infraslow neurofeedback (ISF-NF) on food craving targeting the PCC in obese women with symptoms of food addiction. Participants received six sessions of either ISF-NF (n = 11) or placebo (n = 10) over a three-week period. There were no reported adverse effects. Electrophysiologically, there were significant increases in infraslow activity (p = 0.0002) and infraslow/beta nesting (p < 0.001) in the PCC in the ISF-NF group (mean r = 0.004 ± 0.002) compared to placebo (mean r = 0.02 ± 0.002) two days after the last intervention. Also, there was a significant decrease in different dimensions of state food craving compared to baseline and to placebo. Findings suggest that source localized IFS-NF results in electrophysiological changes and may be associated with reduced food craving. This trial is registered at www.anzctr.org.au , identifier, ACTRN12617000601336. This study was funded by the Otago Medical Research Grant CT375.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Neurorretroalimentação
/
Fissura
/
Giro do Cíngulo
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
Idioma:
En
Revista:
Sci Rep
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Nova Zelândia