Cordycepin induces apoptosis in human pancreatic cancer cells via the mitochondrial-mediated intrinsic pathway and suppresses tumor growth in vivo.

Zhang, Yu; Zhang, Xiao Xi; Yuan, Rui Yan; Ren, Tai; Shao, Zi Yu; Wang, Hong Fei; Cai, Wei Long; Chen, Li Tian; Wang, Xu An; Wang, Ping

Zhang, Yu; Zhang, Xiao Xi; Yuan, Rui Yan; Ren, Tai; Shao, Zi Yu; Wang, Hong Fei; Cai, Wei Long; Chen, Li Tian; Wang, Xu An; Wang, Ping.

Afiliação

Zhang Y; Shanghai Key Laboratory of Biliary Tract Disease Research, Xinhua Hospital, Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, People's Republic of China, chenlitian@xinhuamed.com.cn.
Zhang XX; Department of General Surgery, Hangzhou First People's Hospital, Hangzhou 310006, People's Republic of China.
Yuan RY; Shanghai Health Development Research Center, Shanghai 200040, People's Republic of China.
Ren T; Shanghai Key Laboratory of Biliary Tract Disease Research, Xinhua Hospital, Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, People's Republic of China, chenlitian@xinhuamed.com.cn.
Shao ZY; Department of General Surgery and Laboratory of General Surgery, Xinhua Hospital, Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, People's Republic of China, chenlitian@xinhuamed.com.cn, wangxuan@xinhuamed.com.cn.
Wang HF; Shanghai Key Laboratory of Biliary Tract Disease Research, Xinhua Hospital, Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, People's Republic of China, chenlitian@xinhuamed.com.cn.
Cai WL; Department of General Surgery and Laboratory of General Surgery, Xinhua Hospital, Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, People's Republic of China, chenlitian@xinhuamed.com.cn, wangxuan@xinhuamed.com.cn.
Chen LT; Shanghai Key Laboratory of Biliary Tract Disease Research, Xinhua Hospital, Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, People's Republic of China, chenlitian@xinhuamed.com.cn.
Wang XA; Department of General Surgery and Laboratory of General Surgery, Xinhua Hospital, Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, People's Republic of China, chenlitian@xinhuamed.com.cn, wangxuan@xinhuamed.com.cn.
Wang P; Shanghai Key Laboratory of Biliary Tract Disease Research, Xinhua Hospital, Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, People's Republic of China, chenlitian@xinhuamed.com.cn.

Onco Targets Ther ; 11: 4479-4490, 2018.

Article em En | MEDLINE | ID: mdl-30122940

Palavras-chave

apoptosis; cordycepin; mitochondrial pathway; pancreatic cancer; proliferation

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Onco Targets Ther Ano de publicação: 2018 Tipo de documento: Article