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Assessment of an In Silico Mechanistic Model for Proarrhythmia Risk Prediction Under the CiPA Initiative.
Li, Zhihua; Ridder, Bradley J; Han, Xiaomei; Wu, Wendy W; Sheng, Jiansong; Tran, Phu N; Wu, Min; Randolph, Aaron; Johnstone, Ross H; Mirams, Gary R; Kuryshev, Yuri; Kramer, James; Wu, Caiyun; Crumb, William J; Strauss, David G.
Afiliação
  • Li Z; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Ridder BJ; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Han X; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Wu WW; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Sheng J; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Tran PN; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Wu M; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Randolph A; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Johnstone RH; Department of Computer Science, Healthcare Informatics, University of Oxford, Oxford, UK.
  • Mirams GR; Centre for Mathematical Medicine & Biology, School of Mathematical Sciences, University of Nottingham, Nottingham, UK.
  • Kuryshev Y; Charles River Laboratories, Wilmington, Massachusetts, USA.
  • Kramer J; Charles River Laboratories, Wilmington, Massachusetts, USA.
  • Wu C; Charles River Laboratories, Wilmington, Massachusetts, USA.
  • Crumb WJ; CytoBioscience, New Orleans, Louisiana, USA.
  • Strauss DG; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Clin Pharmacol Ther ; 105(2): 466-475, 2019 02.
Article em En | MEDLINE | ID: mdl-30151907
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Clin Pharmacol Ther Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Clin Pharmacol Ther Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos