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The Way to Ultrafast, High-Throughput Enantioseparations of Bioactive Compounds in Liquid and Supercritical Fluid Chromatography.
Ismail, Omar H; Felletti, Simona; Luca, Chiara De; Pasti, Luisa; Marchetti, Nicola; Costa, Valentina; Gasparrini, Francesco; Cavazzini, Alberto; Catani, Martina.
Afiliação
  • Ismail OH; Department of Drug Chemistry and Technology, "Sapienza" University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy. omar.ismail@uniroma1.it.
  • Felletti S; Department of Chemistry and Pharmaceutical Sciences, University of Ferrara, via L. Borsari 46, 44121 Ferrara, Italy. simona.felletti@unife.it.
  • Luca C; Department of Chemistry and Pharmaceutical Sciences, University of Ferrara, via L. Borsari 46, 44121 Ferrara, Italy. chiara.deluca@unife.it.
  • Pasti L; Department of Chemistry and Pharmaceutical Sciences, University of Ferrara, via L. Borsari 46, 44121 Ferrara, Italy. psu@unife.it.
  • Marchetti N; Department of Chemistry and Pharmaceutical Sciences, University of Ferrara, via L. Borsari 46, 44121 Ferrara, Italy. nicola.marchetti@unife.it.
  • Costa V; Department of Chemistry and Pharmaceutical Sciences, University of Ferrara, via L. Borsari 46, 44121 Ferrara, Italy. valentina.costa@unife.it.
  • Gasparrini F; Department of Drug Chemistry and Technology, "Sapienza" University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy. francesco.gasparrini@uniroma1.it.
  • Cavazzini A; Department of Chemistry and Pharmaceutical Sciences, University of Ferrara, via L. Borsari 46, 44121 Ferrara, Italy. cvz@unife.it.
  • Catani M; Department of Chemistry and Pharmaceutical Sciences, University of Ferrara, via L. Borsari 46, 44121 Ferrara, Italy. ctnmtn@unife.it.
Molecules ; 23(10)2018 Oct 20.
Article em En | MEDLINE | ID: mdl-30347852
ABSTRACT
Until less than 10 years ago, chiral separations were carried out with columns packed with 5 or 3 µ m fully porous particles (FPPs). Times to resolve enantiomeric mixtures were easily larger than 30 min, or so. Pushed especially by stringent requirements from medicinal and pharmaceutical industries, during the last years the field of chiral separations by liquid chromatography has undergone what can be defined a "true revolution". With the purpose of developing ever faster and efficient method of separations, indeed, very efficient particle formats, such as superficially porous particles (SPPs) or.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Cromatografia Líquida / Cromatografia com Fluido Supercrítico / Compostos Fitoquímicos Idioma: En Revista: Molecules Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Itália
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Cromatografia Líquida / Cromatografia com Fluido Supercrítico / Compostos Fitoquímicos Idioma: En Revista: Molecules Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Itália