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A chemical genetic screen reveals that iminosugar inhibitors of plant glucosylceramide synthase inhibit root growth in Arabidopsis and cereals.
Rugen, Michael D; Vernet, Mathieu M J L; Hantouti, Laila; Soenens, Amalia; Andriotis, Vasilios M E; Rejzek, Martin; Brett, Paul; van den Berg, Richard J B H N; Aerts, Johannes M F G; Overkleeft, Hermen S; Field, Robert A.
Afiliação
  • Rugen MD; Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.
  • Vernet MMJL; Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.
  • Hantouti L; Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.
  • Soenens A; Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.
  • Andriotis VME; Centro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, Pozuelo de Alarcón, Madrid, Spain.
  • Rejzek M; Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.
  • Brett P; School of Natural and Environmental Sciences, Devonshire Building, Newcastle University, Newcastle-upon-Tyne, NE1 7RU, UK.
  • van den Berg RJBHN; Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.
  • Aerts JMFG; Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.
  • Overkleeft HS; Leiden Institute of Chemistry, Gorlaeus Laboratories, Leiden University, Einsteinweg 55, 2300 RA, Leiden, The Netherlands.
  • Field RA; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands.
Sci Rep ; 8(1): 16421, 2018 11 06.
Article em En | MEDLINE | ID: mdl-30401902

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Grão Comestível / Arabidopsis / Raízes de Plantas / Eragrostis / Açúcares / Glucosiltransferases Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Grão Comestível / Arabidopsis / Raízes de Plantas / Eragrostis / Açúcares / Glucosiltransferases Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido