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Chemical constituents from the whole herb of Hemiphragma heterophyllum.
Dai, Jia-Meng; Li, Yan-Hong; Pu, Xiao-Yun; Yang, Cui; Sun, Jing-Xian; Ruan, Roger; Li, Xiao-Nian; Tian, Kai; Huang, Xiang-Zhong.
Afiliação
  • Dai JM; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, School of Ethnomedicine and Ethnopharmacy , Yunnan Minzu University , Kunming 650500 , China.
  • Li YH; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, School of Ethnomedicine and Ethnopharmacy , Yunnan Minzu University , Kunming 650500 , China.
  • Pu XY; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, School of Ethnomedicine and Ethnopharmacy , Yunnan Minzu University , Kunming 650500 , China.
  • Yang C; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, School of Ethnomedicine and Ethnopharmacy , Yunnan Minzu University , Kunming 650500 , China.
  • Sun JX; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, School of Ethnomedicine and Ethnopharmacy , Yunnan Minzu University , Kunming 650500 , China.
  • Ruan R; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, School of Ethnomedicine and Ethnopharmacy , Yunnan Minzu University , Kunming 650500 , China.
  • Li XN; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, School of Ethnomedicine and Ethnopharmacy , Yunnan Minzu University , Kunming 650500 , China.
  • Tian K; b State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.
  • Huang XZ; a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, School of Ethnomedicine and Ethnopharmacy , Yunnan Minzu University , Kunming 650500 , China.
J Asian Nat Prod Res ; 21(6): 551-558, 2019 Jun.
Article em En | MEDLINE | ID: mdl-30415578
Phytochemical investigation on Hemiphragma heterophyllum led to the isolation of two new compounds, heterophyllumin A (1) and heterophylliol (3), along with nine known compounds, (‒)-sibiricumin A (2), iridolactone (4), jatamanin A (5), dihydrocatalpolgenin (6), 25-hydroperoxycycloart-23-en-3ß-ol (7), 24-methylenecycloartanol (8), (+)-pinoresinol (9), hexadec-(4Z)-enoic acid (10), and 9,12, 15-octadecatrienoic acid (11). Their structures were elucidated on the basis of detailed spectroscopic analyses and by comparison with literature data. Further, the structure of compound 3 was unambiguously confirmed by single-crystal X-ray analysis. Some of those compounds showed moderate activity in the α-glucosidase inhibition assay.
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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Assunto principal: Compostos de Espiro / Lignanas / Scrophulariaceae / Iridoides Idioma: En Revista: J Asian Nat Prod Res Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Assunto principal: Compostos de Espiro / Lignanas / Scrophulariaceae / Iridoides Idioma: En Revista: J Asian Nat Prod Res Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China