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Leucophyllinines A and B, bisindole alkaloids from Leuconotis eugeniifolia.
Tang, Yiming; Nugroho, Alfarius Eko; Hirasawa, Yusuke; Tougan, Takahiro; Horii, Toshihiro; Hadi, A Hamid A; Morita, Hiroshi.
Afiliação
  • Tang Y; Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-ku, Tokyo, 142-8501, Japan.
  • Nugroho AE; Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-ku, Tokyo, 142-8501, Japan.
  • Hirasawa Y; Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-ku, Tokyo, 142-8501, Japan.
  • Tougan T; Department of Molecular Protozoology, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Horii T; Department of Molecular Protozoology, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Hadi AHA; Department of Chemistry, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia.
  • Morita H; Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-ku, Tokyo, 142-8501, Japan. moritah@hoshi.ac.jp.
J Nat Med ; 73(3): 533-540, 2019 Jun.
Article em En | MEDLINE | ID: mdl-30911994
Two new bisindole alkaloids, leucophyllinines A (1) and B (2) consisting of eburnane and quebrachamine-type skeletons were isolated from the bark of Leuconotis eugeniifolia, and their structures were elucidated on the basis of spectroscopic data. Leucophyllinines A and B showed antiplasmodial activities against Plasmodium falciparum 3D7.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Apocynaceae / Alcaloides Indólicos / Antimaláricos Idioma: En Revista: J Nat Med Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Apocynaceae / Alcaloides Indólicos / Antimaláricos Idioma: En Revista: J Nat Med Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão