Antispasmodic Effect of Essential Oils and Their Constituents: A Review.
Molecules
; 24(9)2019 Apr 29.
Article
em En
| MEDLINE
| ID: mdl-31035694
ABSTRACT
The antispasmodic effect of drugs is used for the symptomatic treatment of cramping and discomfort affecting smooth muscles from the gastrointestinal, billiary or genitourinary tract in a variety of clinical situations.The existing synthetic antispasmodic drugs may cause a series of unpleasant side effects, and therefore the discovery of new molecules of natural origin is an important goal for the pharmaceutical industry. This review describes a series of recent studies investigating the antispasmodic effect of essential oils from 39 plant species belonging to 12 families. The pharmacological models used in the studies together with the mechanistic discussions and the chemical composition of the essential oils are also detailed. The data clearly demonstrate the antispasmodic effect of the essential oils from the aromatic plant species studied. Further research is needed in order to ascertain the therapeutic importance of these findings.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Parassimpatolíticos
/
Óleos Voláteis
Tipo de estudo:
Prognostic_studies
/
Systematic_reviews
Idioma:
En
Revista:
Molecules
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Romênia