Protective effect of a polyphenols-rich extract from Inonotus Sanghuang on bleomycin-induced acute lung injury in mice.

Su, Xing; Liu, Kun; Xie, Yu; Zhang, Mengdi; Wang, Yong; Zhao, Min; Guo, Yilin; Zhang, Yijie; Wang, Junpeng

Su, Xing; Liu, Kun; Xie, Yu; Zhang, Mengdi; Wang, Yong; Zhao, Min; Guo, Yilin; Zhang, Yijie; Wang, Junpeng.

Afiliação

Su X; Institute of Infection and Immunity of Huaihe Hospital, Henan University, Kaifeng, 475000, China.
Liu K; College of Biology Science and Engineering, Hebei University of Economics and Business, Shijiazhuang, Hebei 050061, China.
Xie Y; Institute of Infection and Immunity of Huaihe Hospital, Henan University, Kaifeng, 475000, China; School of Physical Education, Henan University, Kaifeng 475000, China.
Zhang M; Institute of Infection and Immunity of Huaihe Hospital, Henan University, Kaifeng, 475000, China.
Wang Y; Pathology of Huaihe Hospital, Henan University, Kaifeng 475000, China.
Zhao M; Institute of Infection and Immunity of Huaihe Hospital, Henan University, Kaifeng, 475000, China.
Guo Y; Institute of Infection and Immunity of Huaihe Hospital, Henan University, Kaifeng, 475000, China.
Zhang Y; Institute of Infection and Immunity of Huaihe Hospital, Henan University, Kaifeng, 475000, China.
Wang J; Institute of Infection and Immunity of Huaihe Hospital, Henan University, Kaifeng, 475000, China. Electronic address: jpwangchina@henu.edu.cn.

Life Sci ; 230: 208-217, 2019 Aug 01.

Article em En | MEDLINE | ID: mdl-31152815

Assuntos

Lesão Pulmonar Aguda/tratamento farmacológico; Extratos Vegetais/farmacologia; Lesão Pulmonar Aguda/induzido quimicamente; Agaricales/isolamento & purificação; Agaricales/metabolismo; Animais; Antioxidantes/farmacologia; Bleomicina/farmacologia; Líquido da Lavagem Broncoalveolar/citologia; Citocinas/metabolismo; Feminino; Inflamação/patologia; Interleucina-1beta/farmacologia; Pulmão/patologia; Camundongos; Camundongos Endogâmicos C57BL; Fator 2 Relacionado a NF-E2/metabolismo; NF-kappa B/metabolismo; Estresse Oxidativo/efeitos dos fármacos; Phellinus; Polifenóis/isolamento & purificação; Polifenóis/farmacologia; Transdução de Sinais/efeitos dos fármacos; Fator de Necrose Tumoral alfa/farmacologia

Palavras-chave

Acute lung injury; Inflammation; Inonotus sanghuang polyphenols; NF-κB signal; Oxidative stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Lesão Pulmonar Aguda Idioma: En Revista: Life Sci Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

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