Efficacy and safety of periprostatic nerve block combined with perineal subcutaneous anaesthesia and intrarectal lidocaine gel in transrectal ultrasound guided transperineal prostate biopsy: A Prospective Randomised Controlled Trial.
Prostate Cancer Prostatic Dis
; 23(1): 74-80, 2020 03.
Article
em En
| MEDLINE
| ID: mdl-31160805
ABSTRACT
BACKGROUND:
To determine the efficacy and safety of a periprostatic nerve block combined with perineum subcutaneous anaesthesia and intrarectal lidocaine gel for transrectal ultrasound-guided transperineal prostate biopsy (TPBx) through a prospective randomised controlled trial.METHODS:
In total, 216 patients from May 2018 to November 2018 were randomly assigned to the experimental group and the control group at a ratio of 11. The experimental group received a periprostatic nerve block combined with subcutaneous perineal anaesthesia and intrarectal lidocaine gel. The control group received total intravenous anaesthesia. A visual analogue scale (VAS) score (0-10) was used to evaluate pain at different stages. The operative time, duration of hospitalisation, intraoperative vital signs, perioperative complications and clinicopathological features were recorded.RESULTS:
The overall detection rate of prostate cancer was 40.74%, and the median Gleason score was 8 for all patients diagnosed with prostate cancer. No significant differences in terms of detection rates, Gleason scores and ISUP/WHO Grade Groups were found between the two groups (P > 0.05). The experimental group had no pain or just met the criteria for mild pain during the biopsy, which was significantly alleviated after the biopsy, and had a shorter operation time compared with that of the control group (P < 0.05). Compared with the control group, the experimental group had more stable haemodynamics and respiratory status and fewer surgical complications (P < 0.05).CONCLUSIONS:
In multiple aspects, a periprostatic nerve block combined with subcutaneous perineal anaesthesia and intrarectal lidocaine gel is a safer and more efficient approach to local anaesthesia for TPBx that can almost replace total intravenous anaesthesia and is worthwhile applying in the clinical setting.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
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Bloqueio Nervoso Autônomo
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Ultrassom Focalizado Transretal de Alta Intensidade
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Biópsia Guiada por Imagem
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Anestesia Local
Tipo de estudo:
Clinical_trials
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Diagnostic_studies
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Etiology_studies
Idioma:
En
Revista:
Prostate Cancer Prostatic Dis
Ano de publicação:
2020
Tipo de documento:
Article