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MEK inhibitor cobimetinib rescues a dRaf mutant lethal phenotype in Drosophila melanogaster.
Pfeifle, Isabelle; Bohnekamp, Jens; Volkhardt, Anna; Kirsten, Holger; Rohwedder, Astrid; Thum, Andreas; Magin, Thomas M; Kunz, Manfred.
Afiliação
  • Pfeifle I; Department of Dermatology, Venereology and Allergology, University of Leipzig, Leipzig, Germany.
  • Bohnekamp J; Institute of Biology, Division of Cell and Developmental Biology, University of Leipzig, Leipzig, Germany.
  • Volkhardt A; Division of Genetics, Institute of Biology, University of Leipzig, Leipzig, Germany.
  • Kirsten H; Department of Dermatology, Venereology and Allergology, University of Leipzig, Leipzig, Germany.
  • Rohwedder A; Interdisciplinary Center for Bioinformatics and Bioinformatics Group, Department of Computer Science, University of Leipzig, Leipzig, Germany.
  • Thum A; Division of Genetics, Institute of Biology, University of Leipzig, Leipzig, Germany.
  • Magin TM; Division of Genetics, Institute of Biology, University of Leipzig, Leipzig, Germany.
  • Kunz M; Institute of Biology, Division of Cell and Developmental Biology, University of Leipzig, Leipzig, Germany.
Exp Dermatol ; 28(9): 1079-1082, 2019 09.
Article em En | MEDLINE | ID: mdl-31338879
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidinas / Azetidinas / Proteínas Proto-Oncogênicas c-raf / MAP Quinase Quinase Quinases / Proteínas de Drosophila / Drosophila melanogaster Idioma: En Revista: Exp Dermatol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidinas / Azetidinas / Proteínas Proto-Oncogênicas c-raf / MAP Quinase Quinase Quinases / Proteínas de Drosophila / Drosophila melanogaster Idioma: En Revista: Exp Dermatol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha