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Bodyweight-adjusted rivaroxaban for children with venous thromboembolism (EINSTEIN-Jr): results from three multicentre, single-arm, phase 2 studies.
Monagle, Paul; Lensing, Anthonie W A; Thelen, Kirstin; Martinelli, Ida; Male, Christoph; Santamaría, Amparo; Samochatova, Elena; Kumar, Riten; Holzhauer, Susanne; Saracco, Paola; Simioni, Paolo; Robertson, Jeremy; Grangl, Gernot; Halton, Jacqueline; Connor, Phillip; Young, Guy; Molinari, Angelo C; Nowak-Göttl, Ulrike; Kenet, Gili; Kapsa, Stefanie; Willmann, Stefan; Pap, Akos F; Becka, Michael; Twomey, Teresa; Beyer-Westendorf, Jan; Prins, Martin H; Kubitza, Dagmar.
Afiliação
  • Monagle P; Department of Clinical Haematology, Royal Children's Hospital, Haematology Research Murdoch Children's Research Institute, and Department of Paediatrics, University of Melbourne, VIC, Australia.
  • Lensing AWA; Bayer AG, Wuppertal, Germany. Electronic address: anthonie.lensing@bayer.com.
  • Thelen K; Bayer AG, Wuppertal, Germany.
  • Martinelli I; Angelo Bianchi Bonomi Haemophilia and Thrombosis Centre, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
  • Male C; Department of Paediatrics, Medical University of Vienna, Vienna, Austria.
  • Santamaría A; Department of Thrombosis and Haemostasis, University Hospital Vall d'Hebron, Barcelona, Spain.
  • Samochatova E; Federal Research and Clinical Centre of Paediatric Haematology, Oncology and Immunology, Moscow, Russia.
  • Kumar R; Division of Pediatric Hematology and Oncology, Nationwide Children's Hospital, The Ohio State University, Columbus, OH, USA.
  • Holzhauer S; Department of Paediatric Haematology and Oncology, Charité-Universitätsmedizin, Berlin, Germany.
  • Saracco P; Department of Paediatrics, Haematology Unit, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza Torino, Turin, Italy.
  • Simioni P; Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Padova, Italy.
  • Robertson J; Haematology Service, Division of Medicine, Queensland Children's Hospital, South Brisbane, QLD, Australia.
  • Grangl G; Department of Paediatrics and Adolescence Medicine, Division of Paediatric Cardiology, Medical University of Graz, Graz, Austria.
  • Halton J; Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada.
  • Connor P; The Noah's Ark Children's Hospital for Wales, Cardiff, UK.
  • Young G; Keck School of Medicine, University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA, USA.
  • Molinari AC; Thrombosis and Haemostasis Unit, Giannina Gaslini Children's Hospital, Genoa, Italy.
  • Nowak-Göttl U; Thrombosis and Haemostasis Treatment Centre, Institute of Clinical Chemistry, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Kenet G; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Israeli National Haemophilia Centre and Thrombosis Unit and The Amalia Biron Thrombosis Research Institute, Sheba Medical Centre, Tel Hashomer, Israel.
  • Kapsa S; Bayer AG, Wuppertal, Germany.
  • Willmann S; Bayer AG, Wuppertal, Germany.
  • Pap AF; Bayer AG, Wuppertal, Germany.
  • Becka M; Bayer AG, Wuppertal, Germany.
  • Twomey T; Bayer US, Whippany, NJ, USA.
  • Beyer-Westendorf J; Department of Medicine I, Division of Haematology and Haemostaseology, University Hospital Carl Gustav Carus, Dresden, Germany; King's Thrombosis Service, Department of Haematology, King's College London, London, UK.
  • Prins MH; Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Kubitza D; Bayer AG, Wuppertal, Germany.
Lancet Haematol ; 6(10): e500-e509, 2019 Oct.
Article em En | MEDLINE | ID: mdl-31420317
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Texto completo: 1 Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas / Aromoterapia Assunto principal: Tromboembolia Venosa / Rivaroxabana / Anticoagulantes Tipo de estudo: Clinical_trials / Etiology_studies / Guideline / Prognostic_studies Idioma: En Revista: Lancet Haematol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Austrália
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas / Aromoterapia Assunto principal: Tromboembolia Venosa / Rivaroxabana / Anticoagulantes Tipo de estudo: Clinical_trials / Etiology_studies / Guideline / Prognostic_studies Idioma: En Revista: Lancet Haematol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Austrália