Orengedokuto and san'oshashinto improve memory deficits by inhibiting aging-dependent activation of glycogen synthase kinase-3ß.

Fujiwara, Hironori; Yoshida, Jun; Dibwe, Dya Fita; Awale, Suresh; Hoshino, Haruka; Kohama, Hiroshi; Arai, Hiroyuki; Kudo, Yukitsuka; Matsumoto, Kinzo

Fujiwara, Hironori; Yoshida, Jun; Dibwe, Dya Fita; Awale, Suresh; Hoshino, Haruka; Kohama, Hiroshi; Arai, Hiroyuki; Kudo, Yukitsuka; Matsumoto, Kinzo.

Afiliação

Fujiwara H; Institute of Natural Medicine, University of Toyama, Toyama, Japan.
Yoshida J; Institute of Natural Medicine, University of Toyama, Toyama, Japan.
Dibwe DF; Institute of Natural Medicine, University of Toyama, Toyama, Japan.
Awale S; Institute of Natural Medicine, University of Toyama, Toyama, Japan.
Hoshino H; Institute of Natural Medicine, University of Toyama, Toyama, Japan.
Kohama H; Institute of Natural Medicine, University of Toyama, Toyama, Japan.
Arai H; Department of Geriatric and Respiratory Medicine, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Kudo Y; Department of Geriatric and Respiratory Medicine, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Matsumoto K; Institute of Natural Medicine, University of Toyama, Toyama, Japan.

J Tradit Complement Med ; 9(4): 328-335, 2019 Oct.

Article em En | MEDLINE | ID: mdl-31453129

Palavras-chave

AD, Alzheimer's disease; Alzheimer's disease; BPSD, behavioral and psychological symptoms of dementia; CFT, conditioned fear memory test; CRMP2, collapsin response mediator protein-2; Collapsin response mediator protein-2; GSK-3ß, glycogen synthase kinase-3ß; Glycogen synthase kinase-3ß; OGT, orengedokuto; ORT, object recognition test; Orengedokuto; SAMP8, senescence-accelerated prone mice 8; SAMR1, senescence-accelerated prone mice-resistant; SST, san'oshashinto; san'oshashinto

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: J Tradit Complement Med Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão