Four new corynanthe-type alkaloids from the roots of Alstonia scholaris.
Chin J Nat Med
; 17(12): 918-923, 2019 Dec.
Article
em En
| MEDLINE
| ID: mdl-31882046
ABSTRACT
Four new corynanthe-type alkaloids, meloslines C-F (1-4), together with four known ones (5-8) were isolated from the roots of Alstonia scholaris. Their structures including absolute configurations were elucidated by extensive spectroscopic analysis and electronic circular dichroism (ECD) calculation. Compounds 1 and 2 exhibited potent vasorelaxant activity on endothelium-intact renal arteries precontracted with KCl.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Vasodilatadores
/
Raízes de Plantas
/
Alstonia
/
Pausinystalia
/
Alcaloides
País/Região como assunto:
Asia
Idioma:
En
Revista:
Chin J Nat Med
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
China