The protective effect of cordyceps sinensis extract on cerebral ischemic injury via modulating the mitochondrial respiratory chain and inhibiting the mitochondrial apoptotic pathway.

Bai, Xue; Tan, Tian-Yang; Li, Yun-Xin; Li, Yue; Chen, Ya-Fei; Ma, Ru; Wang, Shu-Yan; Li, Qiang; Liu, Zhen-Quan

Bai, Xue; Tan, Tian-Yang; Li, Yun-Xin; Li, Yue; Chen, Ya-Fei; Ma, Ru; Wang, Shu-Yan; Li, Qiang; Liu, Zhen-Quan.

Afiliação

Bai X; Chinese Materia Medica School, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Tan TY; Traditional Chinese Medicine School, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Li YX; Traditional Chinese Medicine School, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Li Y; Chinese Materia Medica School, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Chen YF; Traditional Chinese Medicine School, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Ma R; Chinese Materia Medica School, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Wang SY; Traditional Chinese Medicine School, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Li Q; Chinese Materia Medica School, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Liu ZQ; Chinese Materia Medica School, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China. Electronic address: lzqbzy@sina.com.

Biomed Pharmacother ; 124: 109834, 2020 Apr.

Article em En | MEDLINE | ID: mdl-31978767

Assuntos

Isquemia Encefálica/prevenção & controle; Cordyceps/química; Extratos Vegetais/farmacologia; Acidente Vascular Cerebral/prevenção & controle; Animais; Apoptose/efeitos dos fármacos; Isquemia Encefálica/fisiopatologia; Modelos Animais de Doenças; Transporte de Elétrons/efeitos dos fármacos; Infarto da Artéria Cerebral Média; Masculino; Potencial da Membrana Mitocondrial/efeitos dos fármacos; Camundongos; Mitocôndrias/efeitos dos fármacos; Mitocôndrias/metabolismo; Fármacos Neuroprotetores/isolamento & purificação; Fármacos Neuroprotetores/farmacologia; Ratos Sprague-Dawley; Acidente Vascular Cerebral/fisiopatologia

Palavras-chave

Cerebral is chemic injury; Cordyceps sinensis; Mitochondrial apoptotic pathway; Mitochondrial respiratory chain

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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Assunto principal: Extratos Vegetais / Isquemia Encefálica / Acidente Vascular Cerebral / Cordyceps Tipo de estudo: Prognostic_studies Idioma: En Revista: Biomed Pharmacother Ano de publicação: 2020 Tipo de documento: Article

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