Metabolomics profiling reveals Echinops latifolius Tausch improves the trabecular micro-architecture of ovariectomized rats mainly via intervening amino acids and glycerophospholipids metabolism.

Wang, Jiaqi; Dong, Xin; Ma, Feixiang; Li, Chunyan; Bu, Ren; Lu, Jingkun; Gao, Jianping; Xue, Peifeng

Wang, Jiaqi; Dong, Xin; Ma, Feixiang; Li, Chunyan; Bu, Ren; Lu, Jingkun; Gao, Jianping; Xue, Peifeng.

Afiliação

Wang J; Department of Pharmacy, Inner Mongolia Medical University, Jinshan Development Zone, Hohhot, 010110, China.
Dong X; Department of Pharmacy, Inner Mongolia Medical University, Jinshan Development Zone, Hohhot, 010110, China.
Ma F; Department of Pharmacy, Inner Mongolia Medical University, Jinshan Development Zone, Hohhot, 010110, China.
Li C; Department of Pharmacy, Inner Mongolia Medical University, Jinshan Development Zone, Hohhot, 010110, China.
Bu R; Department of Pharmacy, Inner Mongolia Medical University, Jinshan Development Zone, Hohhot, 010110, China.
Lu J; Department of Pharmacy, Inner Mongolia Medical University, Jinshan Development Zone, Hohhot, 010110, China.
Gao J; Department of Pharmacy, Inner Mongolia Medical University, Jinshan Development Zone, Hohhot, 010110, China. Electronic address: 1067429131@qq.com.
Xue P; Department of Pharmacy, Inner Mongolia Medical University, Jinshan Development Zone, Hohhot, 010110, China. Electronic address: Xpfdc153@163.com.

J Ethnopharmacol ; 260: 113018, 2020 Oct 05.

Article em En | MEDLINE | ID: mdl-32502650

Assuntos

Echinops (Planta)/química; Metabolômica; Osteoporose Pós-Menopausa/tratamento farmacológico; Extratos Vegetais/farmacologia; Aminoácidos/metabolismo; Animais; Biomarcadores/metabolismo; Modelos Animais de Doenças; Progressão da Doença; Feminino; Glicerofosfolipídeos/metabolismo; Humanos; Medicina Tradicional Chinesa; Osteoporose Pós-Menopausa/metabolismo; Osteoporose Pós-Menopausa/patologia; Ovariectomia; Ratos; Ratos Wistar

Palavras-chave

Echinops latifolius Tausch; Metabolomics; Ovariectomized; Trabecular micro-architecture

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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas Assunto principal: Extratos Vegetais / Osteoporose Pós-Menopausa / Echinops (Planta) / Metabolômica Tipo de estudo: Diagnostic_studies Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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