Mechanism of synergistic DNA damage induced by caffeic acid phenethyl ester (CAPE) and Cu(II): Competitive binding between CAPE and DNA with Cu(II)/Cu(I).

Shao, Bo; Mao, Li; Shao, Jie; Huang, Chun-Hua; Qin, Li; Huang, Rong; Sheng, Zhi-Guo; Cao, Dong; Zhang, Zhao-Qiang; Lin, Li; Zhang, Chun-Zhi; Zhu, Ben-Zhan

Shao, Bo; Mao, Li; Shao, Jie; Huang, Chun-Hua; Qin, Li; Huang, Rong; Sheng, Zhi-Guo; Cao, Dong; Zhang, Zhao-Qiang; Lin, Li; Zhang, Chun-Zhi; Zhu, Ben-Zhan.

Afiliação

Shao B; School of Public Health, Jining Medical University, Jining, Shandong, 272067, PR China; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences and University of Chinese Academy of Sciences, The Chinese Academy of Sciences, Beijing, 100085, P
Mao L; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences and University of Chinese Academy of Sciences, The Chinese Academy of Sciences, Beijing, 100085, PR China.
Shao J; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences and University of Chinese Academy of Sciences, The Chinese Academy of Sciences, Beijing, 100085, PR China.
Huang CH; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences and University of Chinese Academy of Sciences, The Chinese Academy of Sciences, Beijing, 100085, PR China.
Qin L; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences and University of Chinese Academy of Sciences, The Chinese Academy of Sciences, Beijing, 100085, PR China.
Huang R; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences and University of Chinese Academy of Sciences, The Chinese Academy of Sciences, Beijing, 100085, PR China.
Sheng ZG; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences and University of Chinese Academy of Sciences, The Chinese Academy of Sciences, Beijing, 100085, PR China.
Cao D; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences and University of Chinese Academy of Sciences, The Chinese Academy of Sciences, Beijing, 100085, PR China.
Zhang ZQ; School of Public Health, Jining Medical University, Jining, Shandong, 272067, PR China.
Lin L; School of Public Health, Jining Medical University, Jining, Shandong, 272067, PR China.
Zhang CZ; School of Public Health, Jining Medical University, Jining, Shandong, 272067, PR China.
Zhu BZ; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences and University of Chinese Academy of Sciences, The Chinese Academy of Sciences, Beijing, 100085, PR China; Joint Institute for Environmental Science, Research Center for Eco-Environmenta

Free Radic Biol Med ; 159: 107-118, 2020 11 01.

Article em En | MEDLINE | ID: mdl-32755670

Assuntos

Peróxido de Hidrogênio; Álcool Feniletílico; Animais; Ligação Competitiva; Ácidos Cafeicos; Cobre; DNA/genética; Dano ao DNA; Álcool Feniletílico/análogos & derivados

Palavras-chave

Caffeic acid phenethyl ester; Competitive binding mechanism; Cu(II); DNA strand breakage; Hydroxyl radical

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Álcool Feniletílico / Peróxido de Hidrogênio Idioma: En Revista: Free Radic Biol Med Ano de publicação: 2020 Tipo de documento: Article

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