The Effect of Estrogen on Intracellular Ca<sup>2+</sup> and Na<sup>+</sup> Regulation in Heart Failure.

Firth, Jahn M; Yang, Hsiang-Yu; Francis, Alice J; Islam, Najah; MacLeod, Kenneth T

The Effect of Estrogen on Intracellular Ca²⁺ and Na⁺ Regulation in Heart Failure.

Firth, Jahn M; Yang, Hsiang-Yu; Francis, Alice J; Islam, Najah; MacLeod, Kenneth T.

Afiliação

Firth JM; National Heart and Lung Institute, Imperial College, Hammersmith Hospital, London, United Kingdom.
Yang HY; Cardiovascular Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan (R.O.C.).
Francis AJ; National Heart and Lung Institute, Imperial College, Hammersmith Hospital, London, United Kingdom.
Islam N; National Heart and Lung Institute, Imperial College, Hammersmith Hospital, London, United Kingdom.
MacLeod KT; National Heart and Lung Institute, Imperial College, Hammersmith Hospital, London, United Kingdom.

JACC Basic Transl Sci ; 5(9): 901-912, 2020 Sep.

Article em En | MEDLINE | ID: mdl-33015413

Palavras-chave

AC, aortic constriction; ACOV+E, aortic constriction with ovariectomy, supplemented with 17ß-estradiol; ACOV, aortic constriction with ovariectomy; FS, fractional shortening; ICa, l-type Ca2+ channel current (cadmium-sensitive); INa,L, late Na+ current (ranolazine-sensitive); NCX, Na+/Ca2+ exchange; OV, ovariectomy; SERCA, Sarco/endoplasmic reticulum Ca2+-ATPase; SR, sarcoplasmic reticulum; calcium regulation; cardiomyocytes; estrogen; excitation-contraction coupling; female; heart failure

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: JACC Basic Transl Sci Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido

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