Anti-Proliferative and Pro-Apoptotic Effects of <i>Calligonum comosum</i> (L'Her.) Methanolic Extract in Human Triple-Negative MDA-MB-231 Breast Cancer Cells.

Alehaideb, Zeyad; AlGhamdi, Saleh; Yahya, Wesam Bin; Al-Eidi, Hamad; Alharbi, Mashael; Alaujan, Monira; Albaz, Abeer; Tukruni, Muruj; Nehdi, Atef; Abdulla, Maha-Hamadien; Matou-Nasri, Sabine

Anti-Proliferative and Pro-Apoptotic Effects of Calligonum comosum (L'Her.) Methanolic Extract in Human Triple-Negative MDA-MB-231 Breast Cancer Cells.

Alehaideb, Zeyad; AlGhamdi, Saleh; Yahya, Wesam Bin; Al-Eidi, Hamad; Alharbi, Mashael; Alaujan, Monira; Albaz, Abeer; Tukruni, Muruj; Nehdi, Atef; Abdulla, Maha-Hamadien; Matou-Nasri, Sabine.

Afiliação

Alehaideb Z; Cell and Gene Therapy Group, Medical Genomics Research Department, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
AlGhamdi S; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Yahya WB; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Al-Eidi H; Clinical Research Department, Research Center, King Fahad Medical City, Riyadh, Saudi Arabia.
Alharbi M; Cell and Gene Therapy Group, Medical Genomics Research Department, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Alaujan M; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Albaz A; Cell and Gene Therapy Group, Medical Genomics Research Department, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Tukruni M; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Nehdi A; Cell and Gene Therapy Group, Medical Genomics Research Department, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Abdulla MH; King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Matou-Nasri S; Cell and Gene Therapy Group, Medical Genomics Research Department, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.

J Evid Based Integr Med ; 25: 2515690X20978391, 2020.

Article em En | MEDLINE | ID: mdl-33302699

Assuntos

Antineoplásicos Fitogênicos/farmacologia; Fitoterapia; Extratos Vegetais/farmacologia; Polygonaceae; Neoplasias de Mama Triplo Negativas; Antineoplásicos Fitogênicos/uso terapêutico; Apoptose/efeitos dos fármacos; Caspase 3/metabolismo; Catalase/metabolismo; Ciclo Celular; Pontos de Checagem do Ciclo Celular; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Inibidor de Quinase Dependente de Ciclina p21/metabolismo; Citocromos c/metabolismo; Humanos; Potencial da Membrana Mitocondrial; Mitocôndrias/efeitos dos fármacos; Extratos Vegetais/uso terapêutico; Espécies Reativas de Oxigênio/metabolismo; Transdução de Sinais; Neoplasias de Mama Triplo Negativas/tratamento farmacológico; Neoplasias de Mama Triplo Negativas/metabolismo

Palavras-chave

Calligonum comosum; apoptosis; cell cycle; natural products; reactive oxygen species; triple-negative breast cancer

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Texto completo: 1 Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas Assunto principal: Extratos Vegetais / Polygonaceae / Neoplasias de Mama Triplo Negativas / Fitoterapia / Antineoplásicos Fitogênicos Idioma: En Revista: J Evid Based Integr Med Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Arábia Saudita

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