Potency of Tokishakuyakusan in treating preeclampsia: Drug repositioning method by in vitro screening of the Kampo library.

Yagi, Kazunobu; Mimura, Kazuya; Tomimatsu, Takuji; Matsuyama, Tatsuya; Kawanishi, Yoko; Kakigano, Aiko; Nakamura, Hitomi; Endo, Masayuki; Kimura, Tadashi

Yagi, Kazunobu; Mimura, Kazuya; Tomimatsu, Takuji; Matsuyama, Tatsuya; Kawanishi, Yoko; Kakigano, Aiko; Nakamura, Hitomi; Endo, Masayuki; Kimura, Tadashi.

Afiliação

Yagi K; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan.
Mimura K; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan.
Tomimatsu T; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan.
Matsuyama T; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan.
Kawanishi Y; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan.
Kakigano A; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan.
Nakamura H; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan.
Endo M; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan.
Kimura T; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan.

PLoS One ; 15(12): e0244684, 2020.

Article em En | MEDLINE | ID: mdl-33378412

Assuntos

Reposicionamento de Medicamentos; Medicamentos de Ervas Chinesas/farmacologia; Células Endoteliais da Veia Umbilical Humana/efeitos dos fármacos; Medicina Kampo; Fator de Crescimento Placentário/metabolismo; Pré-Eclâmpsia/tratamento farmacológico; Adulto; Sobrevivência Celular/efeitos dos fármacos; Medicamentos de Ervas Chinesas/uso terapêutico; Feminino; Células Endoteliais da Veia Umbilical Humana/metabolismo; Humanos; Gravidez; Trofoblastos/efeitos dos fármacos; Trofoblastos/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china / Medicina_japonesa Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas Assunto principal: Pré-Eclâmpsia / Medicamentos de Ervas Chinesas / Medicina Kampo / Reposicionamento de Medicamentos / Células Endoteliais da Veia Umbilical Humana / Fator de Crescimento Placentário Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: PLoS One Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão

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