A promising biomarker of elevated galanin level in hypothalamus for osteoporosis risk in type 2 diabetes mellitus.

Fang, Penghua; She, Yuqing; Han, Long; Wan, Shiwei; Shang, Wenbin; Zhang, Zhenwen; Min, Wen

Fang, Penghua; She, Yuqing; Han, Long; Wan, Shiwei; Shang, Wenbin; Zhang, Zhenwen; Min, Wen.

Afiliação

Fang P; Key Laboratory for Metabolic Diseases in Chinese Medicine, First College of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China; Department of Physiology, Hanlin College, Nanjing University of Chinese Medicine, Taizhou 225300, China.
She Y; Department of Endocrinology, Pukou Branch of Jiangsu People's Hospital, Nanjing 211808, China.
Han L; Key Laboratory for Metabolic Diseases in Chinese Medicine, First College of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Wan S; Key Laboratory for Metabolic Diseases in Chinese Medicine, First College of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Shang W; Key Laboratory for Metabolic Diseases in Chinese Medicine, First College of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Zhang Z; Department of Endocrinology, Clinical Medical College, Yangzhou University, Yangzhou 225001, China. Electronic address: physiolpep@sina.cn.
Min W; Key Laboratory for Metabolic Diseases in Chinese Medicine, First College of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electronic address: wenge1977@126.com.

Mech Ageing Dev ; 194: 111427, 2021 03.

Article em En | MEDLINE | ID: mdl-33383074

Assuntos

Diabetes Mellitus Tipo 2/complicações; Galanina/metabolismo; Hipotálamo/metabolismo; Osteoporose/etiologia; Animais; Biomarcadores/metabolismo; Densidade Óssea; Conservadores da Densidade Óssea/uso terapêutico; Diabetes Mellitus Tipo 2/tratamento farmacológico; Diabetes Mellitus Tipo 2/metabolismo; Diabetes Mellitus Tipo 2/fisiopatologia; Galanina/antagonistas & inibidores; Humanos; Hipoglicemiantes/uso terapêutico; Hipotálamo/fisiopatologia; Resistência à Insulina; Osteoporose/tratamento farmacológico; Osteoporose/metabolismo; Osteoporose/fisiopatologia; Receptor Tipo 2 de Galanina/antagonistas & inibidores; Receptor Tipo 2 de Galanina/metabolismo; Fatores de Risco; Regulação para Cima

Palavras-chave

Bone metabolism; Galanin; Osteoporosis; Type 2 diabetes

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoporose / Galanina / Diabetes Mellitus Tipo 2 / Hipotálamo Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Mech Ageing Dev Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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